While solid organ transplantation is the most effective form of therapy for the treatment of patients with end-stage renal disease (ESRD), 5 concern about the consequences of AMR remains a significant obstacle to transplantation, as it results in significant delays for affected patients to access a suitable transplant. Overall, ESRD patients on dialysis have a very high mortality rate since approximately 65% of these patients die within 5 years of commencing dialysis. 6 Additionally, approximately one-third of patients on the kidney transplant waiting list are sensitized to their potential donors 7 and historically, approximately 30% of this highly sensitized population has developed AMR. 2 A therapy that prevents acute AMR is critically important for sensitized patients with ESRD. Currently, there are no approved therapies for the prevention of acute AMR.About Soliris
Study Evaluating Eculizumab (Soliris®) In Preventing Antibody-Mediated Rejection (AMR) In Kidney Transplant Recipients Presented At The European Society For Organ Transplantation (ESOT) Annual Congress
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