Aug. 21, 2013
/PRNewswire/ -- TechAtlas Group has announced the release of the latest Hepatitis C (HCV) competitive landscape map. This particular landscape highlights 25 international companies with over 60 drugs and combinations currently on the market and in development.
- Winning the HCV race
- Gilead: the one to beat
- Debate over what is "Good Enough"
- Other nukes
- Leading nuke-less regimens
- Strategic Implications of Worldwide genotype distribution
- HCV all-oral combination timeline
- Competitive positioning and rationale for partnerships and M&A
TechAtlas' analysts have evaluated each clinical asset and combination regimen according to the parameters that dictate their commercial competitiveness, including clinical benefit/risk, cost, patient preference, and reimbursement dynamics. For example, all companies are striving to win the HCV race with an all-oral, genotype-1 or pan-genotypic regimen that is convenient (QD), well-tolerated, highly effective (>90% SVR), as short as possible (12 weeks or less), has few drug-drug interactions (DDI), and works well even in patients with subclinical cirrhosis. Such a regimen could be prescribed by primary physicians with little more information than just a confirmation that the patient has HCV and possibly the viral genotype, allowing far more patients to be treated and cured than the current limited bandwidth of specialists allows, not just in the US and
but also in
, and other countries were HCV is prevalent but where medical care is not as "high-touch". If multiple regimens achieve "optimal" status, or even come close, then the leaders will be at the mercy of followers willing to cut price to gain market share. But there is going to be considerable debate over what is "good enough" such that payors could push for cost-savings without being seen as compromising patient care.
The TechAtlas map graphically presents every HCV-related technology, old and new, in its proper context to clearly show the relationship of competing and complementary products for specific unmet needs and a timeline of upcoming clinical milestones as well as expected earliest sales dates through 2017. This map was built on extensive primary research, including interviews with companies, investors, key opinion leaders in the hepatology and infectious disease community, academic researchers, technical experts, consumers of technologies, and other stakeholders in the field, as well as an exhaustive review of public and proprietary resources.