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Microarray Markets

 

NEW YORK, Aug. 19, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Microarray Markets http://www.reportlinker.com/p096372/Microarray-Markets.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=In_Vitro_DiagnosticMicroarray technologies multiplex and miniaturize the analysis of tens of thousands of molecules for a variety of assays, including drug binding, molecular interactions, enzyme activity and pathway identification. These microarrays, which include DNA microarrays, protein microarrays, tissue microarrays, low complexity microarrays and carbohydrate microarrays, are excellent tools for gene expression profiling, biomarker profiling and diagnostics. Pharmaceutical and biotechnology researchers use microarrays to streamline drug target identification, selection, validation and predictive testing. Rapid growth in the clinical research and diagnostic devices markets holds great potential for applications of microarray technology, including basic research, clinical trials and diagnostic devices. This TriMark Publications reports describes the specific segment of the microarray market aimed at the analysis of proteins and DNA. It examines various microarray platforms and the technologies that are utilized in hospitals, clinics, commercial laboratories and research institutions to detect DNA and proteins for the purpose of drug discovery, disease diagnosis and disease monitoring. This report also examines companies that are actively developing and marketing microarray instrumentation or microarray biochips. Detailed tables and charts with sales forecasts and marketshare data are also included.

1. Overview 71.1 Statement of Report 71.2 Scope of the Report 91.3 Objectives 91.4 Methodology 101.5 Executive Summary 11

2. The Commercial Opportunity for Microarrays 152.1 Markets Served by Microarray Technologies 152.1.1 Basic Research Markets 152.1.2 Translational Medicine Markets 162.1.3 Molecular Diagnostic Markets 162.1.4 Specialized/Applied Markets 192.2 Microarray Market Analysis 192.3 Market Drivers 212.4 Market Restraints for Microarrays 232.5 Key Players and Market Share for Major Players 242.6 Strategic Trends and Competitive Landscape for Microarrays 272.7 Marketing and Distribution 28

3. Microarray Overview 303.1 History of Microarrays 303.2 Genomics and Proteomics 303.2.1 Genetic Variability and Disease 333.3 General Theory of Microarrays 333.3.1 DNA Microarrays 353.4 Protein Microarrays 383.5 Tissue Microarrays 393.6 Low Complexity Microarrays 413.7 Carbohydrate Microarrays 42

4. DNA Microarrays 454.1 DNA Microarray Technology Platforms 454.1.1 Microarray Technology 464.1.2 DNA Microarrays?Experimental Design 464.2 Types of Microarrays and Their Applications 474.2.1 Common Microarray Applications 494.3 Reasons Why Researchers Utilize DNA Microarrays 514.4 Factors for Difficulties Applying DNA Microarray Technology 514.5 Key Attributes of DNA Microarray Software 524.6 Microarray Technology in Treating Disease 534.6.1 High-Throughput Array Technology and Cancer 544.6.2 Microarray-Based Commercial Genotyping Activity 574.7 Commercialization of DNA Microarrays 574.8 Future Directions for DNA Microarray Technology 584.8.1 Microarrays vs. Next-Generation Sequencing 594.9 Emerging Microarray Trends 594.10 Emerging Microarray Applications 604.11 Key Points for Developing Microarray-Based Applications 604.12 Competitive Landscape for DNA Microarrays 61 5. Protein Microarrays 625.1 Types of Protein Microarrays 625.1.1 Forward Phase Microarrays 625.1.2 Reverse Phase Microarrays 635.1.3 Peptoid Arrays 635.1.4 Nucleic Acid Programmable Protein Arrays (NAPPA) 655.1.5 Antibody Microarrays 655.1.6 Classifying Protein Microarrays Based on Application 665.2 Critical Factors for Microarray Content 675.3 Key Findings on the Use of Microarrays 685.4 Advantages and Drivers 685.5 Limitations and Barriers to Commercialization 705.6 Key Experimental Parameters of Protein Microarray Technology 735.7 Reasons Why Researchers Utilize Protein Microarrays 745.8 Factors for Adoption of Protein Microarray Technology 745.9 Top Suppliers of Protein Microarray Slides and Products 755.10 Factors that Influence Sale Decisions 755.11 Future Innovations in Protein Microarray Technology 765.12 Protein Arrays Market Analysis 76

6. Current DNA Microarrays 806.1 Key Players 806.2 High Growth Applications 816.2.1 Microarray-Based Commercial Genotyping Activity 816.2.2 Location Analysis 826.2.3 Tiling Arrays 846.2.4 Epigenetic Mapping Arrays 846.3 Innovations in DNA Microarray Technology 866.4 Will Next-Generation Sequencing Replace DNA Microarray Technology? 87

7. Current Protein Microarrays 907.1 Protein Profiling Microarrays?Antibody Arrays 917.2 Protein Profiling Microarrays?Reverse Phase Microarrays 937.3 Multiplex Sandwich Microarrays?Planar 947.4 Multiplex Sandwich Immunoassays?Bead Based 977.5 Microarrays for Protein Function Studies 997.6 Specialized and High Growth Applications 1017.6.1 Cytokine Arrays 1017.6.2 Whole Proteome Arrays 1027.7 Aptamer Arrays 1037.8 Cell-Free Arrays 1037.9 Protein Nanoarrays 105 8. Technology 1068.1 Production of Microarrays 1068.2 2D versus 3D Technology 1098.3 Substrates and Surface Chemistries 1108.4 Next-Generation Microarrays 1128.5 Detection Methods 1138.6 Instruments 1138.7 Data Management and Informatics in Gene Expression 1158.8 Software and Data Analysis 1158.8.1 Supplier of DNA Microarray Analysis Software 1158.8.2 Satisfaction with Software Features 1158.8.3 Satisfaction with Software 1158.8.4 Supplier Factors in Software Purchase Decision 1168.8.5 SuppliersÍ Role in Improving Data Sharing for DNA Microarrays 116

9. Lab-on-a-Chip Technologies 1179.1 Introduction to Lab-on-a-Chip 1179.2 Lab-on-a-Chip Technology 1189.3 Applications for Lab-on-a-Chip Technology 1209.4 The Advantages of Lab-on-a-Chip Technology 1259.5 Barriers to Widespread Adoption 1259.6 Patent Portfolios 1259.7 Trends and Outlook for Lab-on-a-Chip Technology 1269.8 Key Players in Lab-on-a-Chip Industry 1269.9 Lab-on-a-Chip Market Analysis 128 10. Applications 13010.1 DNA Microarrays in Gene Expression 13010.2 DNA Microarrays in SNP Analysis 13210.3 DNA Microarrays in Cancer 13310.3.1 Cancer and Fusion Genes 13610.4 Protein Microarrays 13610.4.1 Cytokine Applications 13610.4.2 Protein Function 13710.4.3 Protein Microarrays in Personalized Medicine 13710.4.4 Protein-Protein Interactions 13810.5 Target/Biomarker Discovery 13810.6 Drug Discovery and Development (Gene and Protein Microarrays) 14010.7 Clinical Diagnostics (Gene and Protein Microarrays) 14010.8 RNA Microarrays 14210.9 Oligo Microarrays 14210.10 Yeast Microarrays 14310.11 Antibody Arrays 14310.12 Arrays for Toxicogenomics 14310.13 Microbial Applications 14410.14 The Market for Microbial Genotyping Products 145

11. Competitive Landscape 14711.1 The Commercial Microarray Market 14711.2 Sector Consolidation 14911.3 Regulatory Matters 15011.4 Legal Matters 15111.5 Intellectual Property 15111.6 Mergers, Acquisitions and Agreements 153 12. Company Profiles 15512.1 Affymetrix 15512.2 Agilent Technologies, Inc. 15712.3 Arrayit Corporation 15812.4 Applied Microarrays 15912.5 AutoGenomics, Inc. 15912.6 AyoxxA 16012.7 BioCat GmbH 16012.8 BioChain, Inc. 16112.9 BioForce Nanosciences, Inc. 16112.10 BioGenex 16112.11 Biomedical Diagnostics (BMD) 16212.12 Biolog, Inc. 16212.13 bioM_rieux SA 16312.14 Biometrix Technology, Inc. 16312.15 Bio-Rad Laboratories 16312.16 Cancer Genetics, Inc. 16512.17 Cepheid, Inc. 16512.18 Clontech Laboratories, Inc. 16512.19 CombiMatrix Corporation 16512.20 CYBRDI 16612.21 DiagnoSwiss SA 16612.22 Discerna 16612.23 EMD Millipore 16612.24 Eurogentec 16712.25 Exiqon 16712.26 Fluidigm Corporation 16812.27 Gamida for Life Group 17012.28 GE Healthcare 17012.29 GGrace Bio-Labs 17212.30 Greiner Bio-One 17212.31 Healthcare IT, Inc. 17312.32 Great Basin Corporation 17312.33 Gyros AB 17412.34 Illumina, Inc. 17412.35 Imgenex Corp. 17612.36 Immucor 17612.37 InDevR 17712.38 Isu Abxis Co., Ltd. 17712.39 LC Sciences 17712.40 Life Technologies/Applied Biosystems (AB)/Invitrogen 17812.41 Lineagen, Inc. 18112.42 Luminex Corporation 18112.43 Maine Manufacturing, LLC 18312.44 Meso Scale Discovery 18312.45 Microarrays, Inc. 18412.46 Microbionix 18512.47 Mingyuan Medicare Development Company Limited 18512.48 MiraiBio 18612.49 Molecular Devices, LLC 18612.50 Monogram Biosciences 18612.51 Myriad Genetics, Inc. 18712.52 NextGen Sciences PLC 18812.53 One Lambda 18812.54 OriGene Technologies 18812.55 Orla Protein Technologies 18912.56 Oxford Nanopore Technologies Ltd. 18912.57 Oxford Gene Technology 18912.58 PamGene BV 19012.59 Partek, Inc. 19012.60 Pepscan 19012.61 Perkin Elmer, Inc. 19112.62 Phalanx Biotech Group 19212.63 PharmaSeq 19312.64 Platypus Technologies, LLC 19312.65 Protagen AG 19412.66 ProteoGenix 19412.67 ProteinOne, Inc. 19412.68 QIAGEN 19512.69 Radix BioSolutions 19612.70 Randox Laboratories Ltd. 19612.71 R&D Systems 19612.72 RayBiotech 19712.73 Roche NimbleGen, Inc. 19712.74 Sequenom, Inc. 19812.75 Sigma-Aldrich 19812.76 SmartBead Technologies 19912.77 SomaLogic 19912.78 SQI Diagnostics 19912.79 SuperBioChips Laboratories 20012.80 Theranostic Health, Inc. 20012.81 Toray Industries, Inc. 20112.82 Trans Genic, Inc. 20112.83 US Biomax 20112.84 Veredus Laboratories Pte Ltd. 20212.85 Zeptosens 20212.86 Zeus Scientific, Inc. 20212.87 Zyagen 203

INDEX OF FIGURESFigure 2.1: Life Sciences Tools Markets, by Sector Served, 2012 15Figure 2.2: Market Share within the Genetic Tools Market, 2012 18Figure 2.3: Microarray Market Share, by Product Type 20Figure 2.4: Global Market Share for Microarray Markets; by Region 21Figure 3.1: Typical Two-Channel DNA Microarray Experiment 37Figure 4.1: Segment of Double-Stranded DNA Showing the Base-Pair Relationship 46Figure 5.1: Peptoid Arrays as Platforms for Biomarker Discovery 64Figure 6.1: ChIP-on-Chip Experiment 83Figure 6.2: The Choice between NGS and Microarrays: Rating by Application 88Figure 7.1: Biomarker Discovery and Validation 90Figure 7.2: Antibody Microarrays?Sandwich Detection Methods 95Figure 7.3: Cytokines and Growth Factors: Sources of Microarrays for Cytokine Research 102Figure 8.1: Sources of Variation in Microarray Data 114Figure 9.1: A Visual Representation of Lab-on-a-Chip and Related Technologies 118Figure 9.2: Unit Components Making up the Lab-on-a-Chip (LOAC) System 119Figure 9.3: Market Share of Biochips Products by Type, 2013 129Figure 10.1: Toxicogenomics: DNA Microarrays 144Figure 10.2: Microbial Genotyping: Applications for DNA Microarrays 146Figure 11.1: Microarray Patents by Region, up to 2013 151Figure 11.2: Microarray Patents by Year, up to 2013 152INDEX OF TABLESTable 2.1: Key Assay Technologies for Molecular Diagnostics 16Table 2.2: Summary of Molecular Diagnostics Testing Sectors 17Table 2.3: Global Market for Molecular Diagnostics Testing, 2008-2018 17Table 2.4: Global Microarray Market, 2010-2018 19Table 2.5: Global Market size for DNA Microarrays, 2010-2018 20Table 2.6: Microarray Market Drivers 22Table 2.7: Leading Microarray Companies 25Table 2.8: Microarray Market Leaders 26Table 4.1: List of DNA Array Manufacturers 45Table 4.2: Steps in the Design and Implementation of a DNA Microarray Experiment 47Table 4.3: Microarray Applications 50Table 4.4: DNA Microarray Applications 51Table 4.5: List of Open Source and Commercially Available Software for Microarray Analysis 52Table 4.6: Microarray Genetic Testing 57Table 4.7: Microarray Market Barriers 58Table 5.1: List of Commercial Antibody Microarrays 66Table 5.2: Commercially Available Protein Arrays 67Table 5.3: Critical Factors for Microarray Content 67Table 5.4: Top Suppliers of Treated Protein Microarray Surfaces for Self-Printing 75Table 5.5: Top Suppliers of Commercially Available Protein Microarrays 75Table 5.6: Top Suppliers of Protein Microarray Platforms 75Table 5.7: Global Market for Protein Microarrays, 2010-2018 77Table 6.1: Types of DNA Microarrays 85Table 7.1: Companies Offering Cytokine Microarrays 102Table 8.1: Comparison of Microarray Platforms 109Table 8.2: Microarray Instruments Offered by Affymetrix 114Table 9.1: Categories of Biochips 117Table 9.2: Applications of Lab-on-a-Chip Technology in Industry 121Table 9.3: Lab-on-a-Chip Diagnostics 123Table 9.4: Lab-on-a-Chip Patents, by Region, 2013 126Table 9.5: List of Companies with Biochip Programs 127Table 9.6: Global Market Size for Lab-on-a-Chip, 2009-2018 129Table 10.1: HTS Microarray Market Size Projections, 2010-2017 132Table 10.2: Protein Microarrays in Personalized Medicine 138Table 11.1: Main Competitors in the Microarray Market, 2013 148Table 11.2: Microarray Patents for Selected Companies, up to 2013 152: Life Sciences Tools Markets, by Sector Served, 2012 15Figure 2.2: Market Share within the Genetic Tools Market, 2012 18Figure 2.3: Microarray Market Share, by Product Type 20Figure 2.4: Global Market Share for Microarray Markets; by Region 21Figure 3.1: Typical Two-Channel DNA Microarray Experiment 37Figure 4.1: Segment of Double-Stranded DNA Showing the Base-Pair Relationship 46Figure 5.1: Peptoid Arrays as Platforms for Biomarker Discovery 64Figure 6.1: ChIP-on-Chip Experiment 83Figure 6.2: The Choice between NGS and Microarrays: Rating by Application 88Figure 7.1: Biomarker Discovery and Validation 90Figure 7.2: Antibody Microarrays?Sandwich Detection Methods 95Figure 7.3: Cytokines and Growth Factors: Sources of Microarrays for Cytokine Research 102Figure 8.1: Sources of Variation in Microarray Data 114Figure 9.1: A Visual Representation of Lab-on-a-Chip and Related Technologies 118Figure 9.2: Unit Components Making up the Lab-on-a-Chip (LOAC) System 119Figure 9.3: Market Share of Biochips Products by Type, 2013 129Figure 10.1: Toxicogenomics: DNA Microarrays 144Figure 10.2: Microbial Genotyping: Applications for DNA Microarrays 146Figure 11.1: Microarray Patents by Region, up to 2013 151Figure 11.2: Microarray Patents by Year, up to 2013 152INDEX OF TABLESTable 2.1: Key Assay Technologies for Molecular Diagnostics 16Table 2.2: Summary of Molecular Diagnostics Testing Sectors 17Table 2.3: Global Market for Molecular Diagnostics Testing, 2008-2018 17Table 2.4: Global Microarray Market, 2010-2018 19Table 2.5: Global Market size for DNA Microarrays, 2010-2018 20Table 2.6: Microarray Market Drivers 22Table 2.7: Leading Microarray Companies 25Table 2.8: Microarray Market Leaders 26Table 4.1: List of DNA Array Manufacturers 45Table 4.2: Steps in the Design and Implementation of a DNA Microarray Experiment 47Table 4.3: Microarray Applications 50Table 4.4: DNA Microarray Applications 51Table 4.5: List of Open Source and Commercially Available Software for Microarray Analysis 52Table 4.6: Microarray Genetic Testing 57Table 4.7: Microarray Market Barriers 58Table 5.1: List of Commercial Antibody Microarrays 66Table 5.2: Commercially Available Protein Arrays 67Table 5.3: Critical Factors for Microarray Content 67Table 5.4: Top Suppliers of Treated Protein Microarray Surfaces for Self-Printing 75Table 5.5: Top Suppliers of Commercially Available Protein Microarrays 75Table 5.6: Top Suppliers of Protein Microarray Platforms 75Table 5.7: Global Market for Protein Microarrays, 2010-2018 77Table 6.1: Types of DNA Microarrays 85Table 7.1: Companies Offering Cytokine Microarrays 102Table 8.1: Comparison of Microarray Platforms 109Table 8.2: Microarray Instruments Offered by Affymetrix 114Table 9.1: Categories of Biochips 117Table 9.2: Applications of Lab-on-a-Chip Technology in Industry 121Table 9.3: Lab-on-a-Chip Diagnostics 123Table 9.4: Lab-on-a-Chip Patents, by Region, 2013 126Table 9.5: List of Companies with Biochip Programs 127Table 9.6: Global Market Size for Lab-on-a-Chip, 2009-2018 129Table 10.1: HTS Microarray Market Size Projections, 2010-2017 132Table 10.2: Protein Microarrays in Personalized Medicine 138Table 11.1: Main Competitors in the Microarray Market, 2013 148Table 11.2: Microarray Patents for Selected Companies, up to 2013 152

To order this report: In_Vitro_Diagnostic Industry: Microarray Markets_________

Contact Clare: clare@reportlinker.comUS:(339) 368 6001Intl:+1 339 368 6001

SOURCE Reportlinker

Copyright 2011 PR Newswire. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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