When comparing LipiGesic M to a comprehensive list published by the Cleveland Clinic of both over-the-counter and prescription formulations for the treatment of acute migraine headaches, it stands alone as a viable migraine treatment without risk of rebound headache. The extensive list that was published on the Cleveland Clinic website includes: "aspirin, sinus relief medications, acetaminophen, nonsteroidal anti-inflammatory medications (NSAIDs), sedatives for sleep, codeine and prescription narcotics, and over-the-counter combination headache remedies containing caffeine (such as Anacin ®, Excedrin ®, Bayer Select ®, and others)."Other medications commonly associated with rebound headaches are ergotamine preparations (Cafergot ®, Migergot ®, Ergomar ®, Bellergal-S ®, Bel-Phen-Ergot S ®, Phenerbel-S ®, Ercaf ®, Wigraine ® and Cafatine PB ®), butalbital combination analgesics (Goody's Headache Powder ®, Supac ®, Excedrin ®, Fiorinal ®) and opiates (codeine). The triptans – which are migraine-specific medications and include Imitrex ®, Zomig ®, Maxalt ®, Relpax ®, Axert ®, Frova ®, Amerge ®, and Treximet ® – taken more than 2 times per week can also cause rebound headaches." http://my.clevelandclinic.org/disorders/Headaches/hic_Rebound_Headaches.aspx
LipiGesic M Is The Only Recommended First-line Therapy For Acute Migraine That Has No Evidence Of Rebound Headache
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