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R&D 100 Award Goes To Waters ACQUITY UPC2 System

MILFORD, Mass., July 29, 2013 /PRNewswire/ -- Waters Corporation (NYSE: WAT) today announced that R&D Magazine recognized the Waters ® ACQUITY UPC 2™ System as one of "the 100 most technologically significant products introduced into the marketplace over the past year."  

(Logo: http://photos.prnewswire.com/prnh/20110707/NE31586LOGO )

The ACQUITY UPC2  System is the first in a new class of separations tools based on the technology of UltraPerformance Convergence Chromatography™ (UPC 2). As an orthogonal technique to LC and GC, the ACQUITY UPC 2 System is an efficient, robust, and reliable technique that employs compressed carbon dioxide, rather than organic solvents, as the primary mobile phase constituent and thus is a greener alternative for many applications – both chiral and achiral – across many industries.

"We are tremendously proud that the ACQUITY UPC 2 System was recognized by the R&D Magazine 51st annual R&D 100 Awards," said Art Caputo, President, Waters Division.  "Since its introduction, ACQUITY UPC 2 adoption spans all the markets we serve – including pharmaceuticals, food, environmental, chemical materials, and clinical research applications.  More than ever, we are confident that ACQUITY UPC 2 is a broad-based, complementary analytical platform that is taking its place alongside of liquid and gas chromatography as one of the three essential separation technologies for modern laboratory analysis."

Prior awards earned by the ACQUITY UPC 2 System include the 2012 Pittcon Editors Gold Award for best new product, SelectScience.net Scientists' Choice Award for Best New Separations product of 2012, and the Green Innovation Trophy at the 1st Innovation Awards 2013 at Forum LABO& BIOTECH.

About Waters ACQUITY UPC 2 System

UPC 2 Technology is based on the principles of UltraPerformance Convergence Chromatography which employs compressed carbon dioxide as the primary mobile phase constituent. The instrument is based on the robust, reliable low-dispersion design of the Waters ACQUITY UPLC ® platform perfected for use with sub-two-micron particle technology.

The technique is suitable for a diverse range of compounds including most organic-soluble compounds, most salts of organic acids and bases, small lipophilic peptides and non-polar solutes.  It is ideal for structurally similar compounds including chiral entities, diastereomers, enantiomers, positional isomers and structural analogs. Essentially any compound soluble in an organic solvent is a candidate for convergence chromatography. The technique is also compatible with many popular detection modes including the full range of Waters mass spectrometers.

Laboratories purchasing the ACQUITY UPC 2 System are finding it to be ideally suited for chiral separations and a welcome replacement for solvent-hungry normal phase LC.

Helping Laboratories Meet Their Sustainability Objectives.

Laboratory-dependent organizations can consume large amounts of organic solvents that are expensive to purchase and can be twice as expensive to dispose of. Many of these organizations have set aggressive sustainability goals for themselves and are investigating the potential of Waters UPC 2 Technology to help meet them and, in turn, save hundreds of thousands of dollars over time.

For these reasons, interest in the technology is especially intense among firms with large laboratory operations.  In a videotaped interview, Daniel Zimmerli, a senior scientist in the Pharmaceuticals Division at J. Hoffman-LaRoche ( Basel, Switzerland) talked about the potential of UPC 2 Technology to cut solvent usage and, in his estimation, replace normal phase LC in "3 to 5 years".

Technological innovation, and the growth of corporate sustainability initiatives, has played a significant role in the renewed interest in SFC and convergence chromatography. A recent article on UPC2 in Genetic Engineering and Biotechnology News reported that the carbon footprint for manufacturing acetonitrile is substantial. With acetonitrile, a common LC solvent, costing between $300 - $400/four-liter bottle - and more than twice that to dispose of - organizations are taking a second look at their consumption of organic solvents in the laboratory. Carbon dioxide on the other hand is extracted from the atmosphere and vented to it after use. As the article states, carbon dioxide is the "greenest HPLC solvent, hands down."

Since the award competition began in 1962, Waters has won six previous R&D 100 awards for its M6000 HPLC Pump, U6K Injector, High Temperature Gel Permeation Chromatograph, Radial Compression Module, Oasis 96-Well (micro)Elution Extraction Plate, and the ACQUITY UPLC System.

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