This Day On The Street
Continue to site right-arrow
ADVERTISEMENT
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
Cramer's Action Alerts PLUS - See his portfolio and get alerts BEFORE every trade. Learn more NOW!

Navidea Biopharmaceuticals’ NAV4694 β-Amyloid Imaging Agent To Be Used In Alzheimer’s Disease Studies By Australian Imaging, Biomarker & Lifestyle Flagship Study Of Ageing (AIBL)

Navidea Biopharmaceuticals, Inc. (NYSE MKT: NAVB), a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL) plans to switch to using Navidea’s Fluorine-18 labeled β-amyloid imaging candidate, NAV4694, from 11C-labeled Pittsburgh Compound-B (PiB) for its comprehensive research initiative in Alzheimer’s disease and Mild Cognitive Impairment. Dr. Christopher C. Rowe, MD FRACP, Director of the Department of Nuclear Medicine and Centre for PET at Austin Health, Melbourne, Australia, announced the changeover to NAV4694 at the World Wide Alzheimer's Disease Neuroimaging Initiative meeting in Boston, MA.

AIBL, a globally renowned, multi-disciplinary effort to investigate factors impacting the development of Alzheimer’s disease across Australia, has previously employed the widely-recognized PiB compound in its research. PiB is the PET imaging agent prototype for β-amyloid detection, and remains an accepted benchmark standard for studies investigating Alzheimer’s disease and differential diagnoses of dementia. Recently published results from a head-to-head study funded by AstraZeneca that directly compared PiB to NAV4694 demonstrated that NAV4694 displayed imaging characteristics nearly identical to those of PiB. 1

“Recent updates to appropriate use criteria allow for earlier diagnosis and therapeutic intervention in the diagnosis of probable Alzheimer’s disease, and we believe β-amyloid PET imaging will play an increasingly important role for clinicians investigating this disease,” said Dr. Rowe, lead author on the head-to-head study. “As the accepted benchmark β-amyloid imaging agent, PiB has an excellent performance profile, but issues around timing, logistics and costs make its routine use challenging. A β-amyloid imaging agent that is accessible and affordable and that can be reliably interpreted in a variety of clinical settings would be most pragmatic. Our studies with NAV4694 show that it mirrors the performance of PiB, and that we can therefore confidently make this changeover and begin using NAV4694 in our research.”

1 of 3

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Try it NOW
Only $9.95
Try it NOW
14-Days Free
Try it NOW

Check Out Our Best Services for Investors

Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Options Profits

Our options trading pros provide over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • Actionable options commentary and news
  • Real-time trading community
Try it NOW
Try it NOW
Try it NOW
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
SYM TRADE IT LAST %CHG

Markets

DOW 17,659.21 -116.91 -0.66%
S&P 500 2,055.32 -12.57 -0.61%
NASDAQ 4,860.62 -40.2650 -0.82%

Partners Compare Online Brokers

Free Reports

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs