IMPORTANT RISK INFORMATION for Immunoglobulin (IG) Products
Immunoglobulin is made from human plasma and may carry a risk of transmitting infectious agents. Immunoglobulin products have demonstrated the ability to induce severe hypersensitivity reactions, thrombotic events, hemolytic anemia and renal dysfunction, acute renal failure, osmotic nephrosis, and death in pre-disposed patients. Immunoglobulin contains blood group antibodies that may act as hemolysins. Hyperproteinemia, increased serum viscosity, and hyponatremia may occur in patients receiving IG. Aseptic meningitis syndrome has also been reported following intravenous administration of IG. Non-cardiogenic pulmonary edema (TRALI) has been reported in patients following treatment with IG products.
About Baxter International Inc.
Baxter International Inc., through its subsidiaries, develops, manufactures and markets products that save and sustain the lives of people with hemophilia, immune disorders, infectious diseases, kidney disease, trauma and other chronic and acute medical conditions. As a global, diversified healthcare company, Baxter applies a unique combination of expertise in medical devices, pharmaceuticals and biotechnology to create products that advance patient care worldwide.This release includes forward-looking statements concerning the company’s development program investigating the potential use of Baxter IG for the treatment of mild to moderate Alzheimer's disease, including with respect to ongoing additional analyses of the data from the GAP study. The statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those in the forward-looking statements: completion of additional analyses of the data from the GAP study; actions of regulatory bodies and other governmental authorities; the development of other clinical evidence with respect to the treatment of Alzheimer’s disease; and other risks identified in the company's most recent filing on Form 10-K and other SEC filings, all of which are available on the company's website. The company does not undertake to update its forward-looking statements.