LAWRENCEVILLE, N.J., July 11, 2013 /PRNewswire/ -- Celsion Corporation (NASDAQ: CLSN) announced today that Ronnie T.P. Poon, MD, MS, PhD, FRCS(Edin), FACS, Professor of Surgery at the University of Hong Kong and Lead Asia Pacific Principal Investigator for Celsion's Phase III HEAT Study of ThermoDox® in hepatocellular carcinoma (HCC) will present the clinical trial results at the International Liver Cancer Association 7 th Annual Conference being held September 13-15, 2013 in Washington D.C. The presentation will include data from the HEAT Study post hoc analysis, which suggests positive progression free survival (PFS) and overall survival (OS) in ThermoDox® treated patients when heating cycles from the radiofrequency ablation (RFA) procedure were optimized.
Professor Poon's oral presentation, titled "Phase 3 Randomized, Double-Blind, Dummy-Controlled Trial of Radiofrequency Ablation (RFA) + Lyso-Thermosensitive Liposomal Doxorubicin for Hepatocellular Carcinoma (HCC) Lesions 3-7 cm," will be held Saturday, September 14, 2013 at 12:00 p.m. (local time) in the Plenary Session. ILCA has selected the HEAT Study presentation to be webcast as part of an online educational program of the ILCA 2013 Annual Conference. Dr. Poon's presentation will be made available online after the conference.
The International Liver Cancer Association is the only international organization devoted exclusively to liver cancer research for experts from all related disciplines -- medical, interventional and surgical oncology as well as hepatology. ILCA's Executive Committee consists of Dr. Josep M. Llovet (President); Professor Riccardo Lencioni and Dr. Morris Sherman. Professor Lencioni co-chaired a session devoted to radiofrequency ablation at the 2013 European Conference on Interventional Oncology held in Budapest, Hungary on June 19, 2013 during which he discussed the HEAT Study results and the emerging post hoc analysis data. Celsion also notes that Professors Lencioni and Poon and Dr. Sherman are principal investigators on the HEAT Study.
Celsion has conducted a comprehensive analysis of the data from the Phase III HEAT Study of ThermoDox® in HCC, also known as primary liver cancer, with key principal investigators, data experts and liver cancer experts including Professors Lencioni and Poon. Emerging data from the HEAT Study post hoc analysis demonstrates that ThermoDox® markedly improves PFS and overall survival in patients if their lesions undergo RFA for 45 minutes or more. These findings apply to HCC lesions from both size cohorts of the HEAT Study (3-5 cm and 5-7 cm) and represent a sizable subgroup of approximately 300 patients.
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