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ViroPharma Provides Update From Ongoing Phase 2 Studies Of Maribavir For Treatment Of Cytomegalovirus (CMV) Infections

About Cytomegalovirus

CMV is a member of the herpes virus group, which includes the viruses that cause chicken pox, mononucleosis, herpes labialis (cold sores), and herpes genitalis (genital herpes).  Like other herpesviruses, CMV has the ability to remain dormant in the body for long periods of time. Human CMV infection rates average between 50 percent and 85 percent of adults in the U.S. by 40 years of age, but in healthy adults causes little to no apparent illness. However, in immunocompromised individuals including cancer patients, HIV patients, and transplant patients, and in children born with primary CMV infection, CMV can lead to serious disease or death.  Patients who are immunosuppressed following hematopoietic stem cell (bone marrow) or solid organ transplantation are at high risk of CMV infection.  In these patients, CMV can lead to severe conditions such as pneumonitis or hepatitis, or to complications such as acute or chronic rejection of a transplanted organ.  While currently available systemic anti-CMV agents are effective against the virus, their use is limited by toxicities, most notably bone marrow suppression and renal impairment.

About ViroPharma Incorporated

ViroPharma Incorporated is an international biopharmaceutical company committed to developing and commercializing novel solutions for physician specialists to address unmet medical needs of patients living with diseases that have few, if any, clinical therapeutic options, including C1 esterase inhibitor deficiency, treatment of seizures in children and adolescents, adrenal insufficiency, and C. difficile infection (CDI). Our goal is to provide rewarding careers to employees, to create new standards of care in the way serious diseases are treated, and to build international partnerships with the patients, advocates, and healthcare professionals we serve.

ViroPharma routinely posts information, including press releases, which may be important to investors in the investor relations and media sections of our company's website, http://www.viropharma.com/. The company encourages investors to consult these sections for more information on ViroPharma and our business.

Forward-Looking Statements

Certain statements in this press release contain forward-looking statements that involve a number of risks and uncertainties. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. Forward-looking statements in this press release include statements regarding potential therapeutic indication and use of maribavir and regarding maribavir's potential to address unmet medical needs. The development and commercialization of pharmaceutical products is subject to risks and uncertainties. The clinical data included in this press release is preliminary and the study is ongoing. There can be no assurance that the data generated at the end of the studies will be consistent with the preliminary results described in this press release.  In addition, future data generated in this study may elucidate trends not apparent at this time. There can be no assurance that future studies with maribavir will generate positive results or that maribavir will receive regulatory approvals. The FDA or EMA may view data regarding maribavir as insufficient or inconclusive, request additional data, require additional clinical studies, limit any approved indications, or deny the approval of maribavir. A description of risks and uncertainties can be found in ViroPharma's Annual Report on Form 10-K for the fiscal year ended December 31, 2012, and 10-Q for the quarter ended March 31, 2013 filed with the Securities and Exchange Commission. The forward-looking statements contained in this press release are made as of the date hereof and may become outdated over time. ViroPharma does not assume any responsibility for updating any forward-looking statements. These forward-looking statements should not be relied upon as representing our assessments as of any date subsequent to the date of this press release.

 

SOURCE ViroPharma Incorporated

Copyright 2011 PR Newswire. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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