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ThromboGenics' JETREA® Launched In Denmark And Sweden

LEUVEN, Belgium, May 27, 2013 /PRNewswire/ --

Roll out in Finland and Norway to follow shortly

ThromboGenics NV (Euronext Brussels: THR), an integrated biopharmaceutical company focused on developing and commercializing innovative ophthalmic medicines, today announces that its partner Alcon has launched JETREA ® in Denmark and Sweden, the third and fourth European markets where the product is now available. Alcon will roll out the drug in Finland and Norway shortly.

In mid-March 2013, JETREA ® was approved by the European Commission (EC) for the treatment of vitreomacular traction (VMT), including when associated with a macular hole of diameter less than or equal to 400 microns.

Alcon's first European launch of JETREA ® took place in the UK last month, followed by Germany earlier this month. Alcon, a division of Novartis, acquired the rights to commercialize JETREA ® outside the United States in March 2012.  

Under the terms of this deal ThromboGenics has already received €165 million in upfront and milestone payments, including €90 million following EMA approval of JETREA ® and first injection (UK) in patients. The company could receive a further €210 million in milestones plus significant royalties on Alcon's sales of JETREA ®.

ThromboGenics launched JETREA ® in the US in mid-January 2013 where it is approved for the treatment of patients with symptomatic vitreomacular adhesion (VMA). US sales since launch are in line with the Company's expectations.

Dr Patrik De Haes, CEO of ThromboGenics, says:    "We are extremely encouraged by our partner Alcon's rapid progress in making JETREA ®   available across  Europe . We look forward to further launches across the Nordic region and other countries to ensure that patients are able to have access to the first pharmacological treatment for VMT including when associated with a macular hole of diameter less than or equal to 400 microns."      

JETREA ® contains the active substance ocriplasmin. It is administered through a single intravitreal injection to treat adults with vitreomacular traction (VMT).

VMT, which in the US is referred to as symptomatic VMA, is an age-related progressive, sight-threatening condition. It is caused by the vitreous humour having an abnormally strong attachment to the macula, the central part of the retina (the light sensitive membrane at the back of the eye). The macula provides central vision that is needed for everyday tasks such as driving, reading and recognizing faces.

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