This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
Stocks Under $10 with 50-100% upside potential - 14 days FREE!

Boston Scientific Long Term Data Demonstrate Bronchial Thermoplasty Treatment Benefits Persist Out To Five Years In Patients With Severe Asthma

NATICK, Mass., May 21, 2013 /PRNewswire/ -- Five-year data from the Asthma Intervention Research 2 (AIR2) clinical trial presented today demonstrated that the Boston Scientific Corporation (NYSE: BSX) Alair ® Bronchial Thermoplasty (BT) System continues to show therapy benefits in adult patients with severe uncontrolled asthma.  Bronchial Thermoplasty was shown to provide long term asthma control, demonstrated by a sustained reduction in the rate of severe exacerbations (asthma attacks) and emergency room (ER) visits over a five year period after treatment.  The AIR2 trial is the fourth in a series of clinical trials that have completed five years of follow-up and the first to evaluate persistence of effect for patients treated with BT.  Results were presented at the annual meeting of the American Thoracic Society (ATS) in Philadelphia by Michael E. Wechsler, M.D., director of the Asthma Program in the Department of Medicine at National Jewish Health in Denver and an investigator in the AIR2 trial.

"With the availability of the new long term data demonstrating that the benefits of Bronchial Thermoplasty persist for at least five years, I can confidently recommend BT as a therapeutic option to patients whose asthma is poorly controlled with medications alone," said Dr. Wechsler.  "This is very important because minimizing the risk of recurrent asthma attacks and the associated need for oral steroid treatment in this patient population is a primary goal in asthma therapy.  Bronchial Thermoplasty represents a one time, long term option for achieving better asthma control in a select population of patients. Left uncontrolled, these patients contribute to a disproportionate share of the costs associated with treating asthma."

The data are based on an open-label study following BT-treated patients who completed the one-year portion of the AIR2 trial for a total of five years.  The goal of the study was to demonstrate that the percentage of patients experiencing severe exacerbations over the five years following BT was not substantially worse than the percentage of patients having exacerbations in the first year after BT.  The data demonstrated that over five years following BT there was a:

  • 44 percent average decrease in percent of patients having severe exacerbations compared to the year prior to BT
  • 48 percent average decrease in severe exacerbation event rates compared to the year prior to BT
  • 88 percent average decrease in ER visit event rates compared to the year prior to BT

"We are pleased to see the significant benefits of Bronchial Thermoplasty persist out to five years in patients with severe asthma," said David Pierce, president, Endoscopy, Boston Scientific.  "These clinically meaningful improvements demonstrate that Bronchial Thermoplasty improves patient outcomes and quality of life.  In addition, by significantly reducing health care utilization, Bronchial Thermoplasty presents an opportunity to reduce overall health care costs for asthma."

Separately, the Asthma and Allergy Foundation of America (AAFA) recently released its list of 2013 Asthma Capitals, an assessment of the most challenging places to live with asthma in the United States ( http://www.asthmacapitals.com).  For the first time, this year AAFA added a new factor to the ranking assessment:  ER visits for asthma.  About five percent of the asthma population is considered to have the most severe form of asthma and often does not respond well to conventional asthma treatments.  People with severe asthma are likely to have more asthma attacks, visit ERs or be hospitalized more frequently, and are at greater risk of death.

Bronchial Thermoplasty, delivered by the Alair System, is a safe, outpatient procedure proven to provide a long lasting reduction in asthma attacks and ER visits for patients with severe asthma.  The Alair System delivers thermal energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle.  It is designed to decrease the airway's ability to constrict, thereby reducing asthma attack frequency and severity.  Fewer asthma attacks mean less need for the associated oral steroid treatment—and its side effects.  To learn more about Bronchial Thermoplasty, visit www.BTforAsthma.com.

In summary, BT is a novel bronchoscopic procedure providing long lasting asthma control that has demonstrated a strong long term safety and efficacy profile out to at least five years in four consecutive clinical trials. 

1 of 2

Select the service that is right for you!

COMPARE ALL SERVICES
Action Alerts PLUS
Try it NOW

Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
  • Weekly roundups
TheStreet Quant Ratings
Try it NOW
Only $49.95/yr

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
  • Upgrade/downgrade alerts
Stocks Under $10
Try it NOW

David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
  • Weekly roundups
Dividend Stock Advisor
Try it NOW

Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Alerts when market news affect the portfolio
  • Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
Real Money Pro
Try it NOW

All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.

Product Features:
  • Real Money + Doug Kass Plus 15 more Wall Street Pros
  • Intraday commentary & news
  • Ultra-actionable trading ideas
Options Profits
Try it NOW

Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • 100+ monthly options trading ideas
  • Actionable options commentary & news
  • Real-time trading community
  • Options TV
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
DOW 17,113.54 +61.81 0.36%
S&P 500 1,983.53 +9.90 0.50%
NASDAQ 4,456.0160 +31.3120 0.71%

Brokerage Partners

Rates from Bankrate.com

  • Mortgage
  • Credit Cards
  • Auto
Advertising Partners

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs