This Day On The Street
Continue to site
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here

Preclinical Research Shows PLX Cells May Be Effective In Treating Preeclampsia

HAIFA, Israel, May 13, 2013 (GLOBE NEWSWIRE) -- Pluristem Therapeutics Inc. (Nasdaq:PSTI) (TASE:PLTR), a leading developer of placenta-based cell therapies, announced today its PLacental eXpanded (PLX) cells tested in preclinical animal models of preeclampsia effectively improved several parameters of the disease. The study was conducted in collaboration with Brett Mitchel PhD, Associate Professor of Internal Medicine at the Cardiovascular Research Institute (CVRI) of the Texas A&M College of Medicine. Dr. Mitchel will present details of the study on May 30 th at the Society for Gynecological Investigation Summit in Jerusalem.

Preeclampsia is the most common medical complication of pregnancy and a leading cause of premature births, stillbirths and early neonatal and maternal deaths. If left untreated, it can develop into eclampsia, the life-threatening occurrence of seizures during pregnancy. The only known treatment for eclampsia or preeclampsia is abortion or delivery. The disease occurs in previously healthy women after their 20 th week of pregnancy and symptoms include high blood pressure and significant amounts of protein in the urine. According to the World Health Organization, preeclampsia occurs in approximately 6-8% of pregnancies worldwide. It is estimated that preeclampsia costs the global health care system $3 billion annually. May was recognized as National Preeclampsia Awareness Month by U.S. Congresswomen in an effort to improve outcomes for women and babies.

Since preeclampsia is a human pregnancy specific disease, defined as the occurrence of hypertension and significant proteinuria, Dr. Mitchell has established and published two preeclampsia rodent models that exhibits the fundamental features of preeclampsia; pregnancy dependent hypertension and proteinuria. PLX cells administered IM were tested against cell-free medium in these two preeclampsia animal models. Pregnant mice that developed gestational hypertension and proteinuria and received PLX cells demonstrated several positive physiologic, immunologic and histologic findings indicating that PLX cells could be effective in treating preeclampsia.

1 of 3

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Only $9.95
14-Days Free
Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Real Money

More than 30 investing pros with skin in the game give you actionable insight and investment ideas.

Product Features:
  • Access to Jim Cramer's daily blog
  • Intraday commentary and news
  • Real-time trading forums
Only $49.95
14-Days Free
14-Days Free


Chart of I:DJI
DOW 16,472.37 +200.36 1.23%
S&P 500 1,951.36 +27.54 1.43%
NASDAQ 4,707.7750 +80.6910 1.74%

Free Reports

Top Rated Stocks Top Rated Funds Top Rated ETFs