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MediPoint: Total Ankle Replacement - US Analysis And Market Forecasts

Scope- An overview of Ankle arthritis, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.- Annualized US TAR market revenue and future forecasts from 2009 to 2011, forecast for 7 years to 2018.- Investigation of current and future market competition for TAR- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.- Competitor assessment including device approval analysis and device sales forecasts.- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.- Analysis of unmet needs within the market and opportunities for future players.- Technology trends evaluation to assess strength of pipeline.- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.- Company profiles including business description, financial overview and SWOT analysis.- Coverage of key market players.- Strategic assessment of the TAR device sector through market impact analysis, future market scenario and company analysis.- Direct quotes from Key Opinion Leaders (KOL) as well as oncologists

Reasons to buy- Understand the trends shaping and driving the US TAR Market.- Realize device preferences of physicians who have performed the tests already.- Access market sizing, forecasts and quantified growth opportunities in the US TAR Market through 2018.- Quantify candidate patient populations to better design product pricing & launch plans.- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.- Perform benchmarking analysis of growth opportunities against currently marketed products.- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.- Take a comprehensive look at the market's device pipeline and identify promising, paradigm-shifting products.- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.- What's the next big thing in the US TAR market landscape? Identify, understand and capitalize.

Table of Contents1 Table of Contents 61.1 List of Tables 101.2 List of Figures 122 Introduction 132.1 Catalyst 133 Disease Overview 143.1 Anatomy and Physiology 143.2 Pathophysiology 153.2.1 Overview 153.2.2 Post-Traumatic Arthritis 163.2.3 Inflammatory Arthritis 173.2.4 Primary Osteoarthritis 183.2.5 Others 183.3 Clinical Presentation 193.3.1 Symptoms 193.3.2 Diagnosis 203.4 Clinical Outcomes 213.4.1 Overview 213.4.2 Conservative Treatments 213.4.3 Joint-Preserving Surgeries 223.4.4 Definitive Procedures 253.5 Epidemiology 293.5.1 Prevalence 293.5.2 Treatments 303.6 Economic Impact 313.6.1 Economic Impact in the US 324 Competitive Assessment 334.1 Overview 334.2 Competitive Assessment 344.3 US Marketed Products 354.3.1 Scandinavian Total Ankle Replacement (STAR) 354.3.2 Agility LP 374.3.3 Salto Talaris 404.3.4 INBONE II 434.3.5 Zimmer Trabecular Metal Total Ankle 465 Unmet Needs 485.1 Long-Term Follow-Up 495.2 Commitment to Medical Education 505.3 Advanced Biological Fixation 515.4 Minimal Bone Resection 535.4.1 Tibial Component 535.4.2 Talar Component 535.5 Mobile-Bearing versus Fixed-Bearing 545.6 Bespoke Instrumentation 565.7 Custom Prostheses 565.8 Revision Components 576 Pipeline Products 586.1 Overview 586.2 INBONE II Total Ankle with Calcaneal Stem Fixation 586.2.1 Overview 586.2.2 SWOT Analysis 597 Industry Overview 607.1 Procedure Trends 607.2 Market Access 617.2.1 Regulatory Process 617.2.2 Adoption 627.3 Reimbursement Trends 637.4 Regulatory Issues/Recalls 657.4.1 No Custom Devices for DePuy's Agility Total Ankle Prosthesis in the US 657.5 Mergers & Acquisitions/Key Partnerships 668 Current and Future Players 678.1 Overview 678.2 Trends in Corporate Strategy 678.3 Company Profiles 688.3.1 Small Bone Innovation, Inc. 688.3.2 DePuy Synthes 708.3.3 Tornier 728.3.4 Wright Medical Group, Inc. 748.3.5 Zimmer Holdings, Inc. 769 Market Drivers, Opportunities, and Barriers 789.1 Market Drivers 789.1.1 Superiority to Ankle Fusion 789.1.2 Rising Prevalence 809.1.3 Expanded Insurance Coverage 819.1.4 Availability of Long-Term Data 819.1.5 Increased Patient Awareness 829.2 Opportunities 839.2.1 Expanded Indications 839.2.2 Advanced Biological Fixation Approaches 839.2.3 Revision TAR 849.2.4 Demand for Custom Prostheses 849.2.5 Demand for a Comprehensive Foot and Ankle Product Portfolio 859.3 Market Barriers 869.3.1 Preoperative Patient Selection 869.3.2 Long Learning Curve 879.3.3 Complications 889.3.4 Cost 889.3.5 Reimbursement 889.3.6 Substitutes 8910 Country Outlooks and Forecasts 9010.1 US Market Analysis 9011 Appendix 9311.1 Abbreviations 9311.2 Bibliography 9411.3 Methodology 9911.3.1 Coverage 9911.3.2 Secondary Research 9911.3.3 Primary Research 10011.3.4 Forecasting Methodology 10111.4 Physicians and Specialists Included in this Study 10211.5 Physician Survey 10311.6 About the Authors 10311.6.1 Analysts 10311.6.2 Global Head of Healthcare 10411.7 About MediPoint 10411.8 About GlobalData 10411.9 Contact Us 10511.10 Disclaimer 105

List of TablesTable 1: Common Clinical Symptoms of Ankle Arthritis 19Table 2: Indications and Contraindications of TAR 28Table 3: Direct and Indirect Costs of Arthritis 31Table 4: Currently Marketed Total Ankle Replacement Implants 33Table 5: Product Profile – STAR 36Table 6: SWOT Analysis – STAR 36Table 7: Product Profile – Agility LP 38Table 8: SWOT Analysis – Agility LP 39Table 9: Product Profile – Salto Talaris 41Table 10: SWOT Analysis – Salto Talaris 42Table 11: Product Profile – INBONE II 44Table 12: SWOT Analysis – INBONE II 45Table 13: Product Profile – Zimmer Trabecular Metal Total Ankle 47Table 14: SWOT Analysis - Zimmer Trabecular Metal Total Ankle 47Table 15: Overall Unmet Needs – Current Level of Attainment and Importance (n=30) 48Table 16: Coating Methods of Currently Marketed TAR Implants 51Table 17: Product Profile – INBONE II Total Ankle with Calcaneal Stem Fixation 58Table 18: SWOT Analysis of INBONE II Total Ankle with Calcaneal Stem Fixation 59Table 19: 2011 Medicare National Payment Average for Total Ankle Replacement 63Table 20: Company Profile – Small Bone Innovations 68Table 21: Portfolio Assessment – Small Bone Innovations, 2013 68Table 22: SBi's Foot and Ankle Business SWOT Analysis, 2013 69Table 23: Company Profile – DePuy Synthes Companies 70Table 24: DePuy's Total Ankle Replacement Portfolio Assessment, 2013 71Table 25: DePuy's Foot and Ankle Business SWOT Analysis, 2013 71Table 26: Company Profile – Tornier 72Table 27: Tornier's Total Ankle Replacement Portfolio Assessment, 2013 72Table 28: Tornier's Foot and Ankle Business SWOT Analysis, 2013 73Table 29: Company Profile – Wright Medical Group 74Table 30: Wright Medical's Total Ankle Replacement Portfolio Assessment, 2013 75Table 31: Wright Medical's Foot and Ankle Business SWOT Analysis, 2013 75Table 32: Company Profile – Zimmer Holdings 76Table 33: Zimmer Holding's Total Ankle Replacement Portfolio Assessment, 2013 76Table 34: Zimmer's Foot and Ankle Business SWOT Analysis, 2013 77Table 35: Advantages and Disadvantages of Ankle Fusion and Total Ankle Replacement 79Table 36: Sales Forecasts for TAR in the US (2009–2018) 90Table 37: Abbreviations 93

List of FiguresFigure 1: Schematic Diagram of Ankle Anatomy 14Figure 2: Ankle Arthritis Subtypes 15Figure 3: Causes of Post-Traumatic Ankle Arthritis 16Figure 4: Staged Treatment Approach of Ankle Arthritis 21Figure 5: An Example of Ankle Distraction Arthroplasty 24Figure 6: An Example of Ankle Fusion 25Figure 7: An Example of a Total Ankle Replacement Implant 27Figure 8: US Population with Ankle Arthritis (2009–2018) 29Figure 9: Treatment Modalities of Ankle Arthritis in Developed Countries 30Figure 10: Estimated Costs of Ankle Arthritis, 2009–2018 32Figure 11: Product Image – STAR 35Figure 12: Product Image – Agility LP 38Figure 13: Product Image – Salto Talaris 40Figure 14: Product Image – INBONE II 44Figure 15: Product Image – Zimmer Trabecular Metal Total Ankle 46Figure 16: TAR Procedure Volume in the US (2009–2018) 60Figure 17: Sales Forecasts for TAR in the US (2009–2018) 90

Companies MentionedSmall Bone Innovation, Inc.DePuy SynthesTornierWright Medical Group, Inc.Zimmer Holdings, Inc.

To order this report: Orthopedic Industry: MediPoint: Total Ankle Replacement - US Analysis and Market Forecasts

Contact Clare: clare@reportlinker.comUS:(339) 368 6001Intl:+1 339 368 6001

SOURCE Reportlinker

Copyright 2011 PR Newswire. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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