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PharmaPoint: Osteoporosis - China Drug Forecast and Market Analysis to 2022
GlobalData has released its new Country report, "PharmaPoint: Osteoporosis - China Drug Forecast and Market Analysis to 2022". Despite its maturity, the osteoporosis market is expected to undergo substantial change between 2012 and 2022. Most importantly, the 'gold-standard' bisphosphonates will lose patent protection by end-of-year 2013, flooding the marketplace with less expensive generic versions of these physician-preferred medications. Additionally, Eli Lilly's blockbuster Evista, the only available SERM in the US, will lose patent protection in 2014, flooding the market with yet more affordable generic options. Also during the forecast period covered by this report, osteoporosis drug development research will lead to the launches of a wave of novel anabolic drugs with greater efficacy and safety, causing a major market shift away from anti-resorptive drugs. The number of companies vying for patient share will shrink by as much as 50%, as established players exit the market or acquire smaller players. Lastly, the aging of the population in developed markets will result in a larger patient pool.
These changes in the osteoporosis market will be reflected in the slow growth during the forecast period, with the market growing from
$6 billion to $8 billion in
2011 USD at a CAGR of 3%.
India, recession of the market for branded products will be caused by floods of generic products into the market. Like
China will likely start issuing compulsory licenses for Chinese generics companies to violate IP rights and produce drugs prior to patent expiries. Therefore, GlobalData expects the Chinese market to be dominated by generic products, and to lose significant value in the branded side of the drug market. GlobalData did not project the pipeline products launching in the major markets because sales will likely be retarded by generic products.
- Overview of the Osteoporosis including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.- Detailed information on the key drugs in
China including product description, safety and efficacy profiles as well as a SWOT analysis.- Sales forecast for the top drugs in
China from 2012-2022.- Analysis of the impact of key events as well the drivers and restraints affecting China Osteoporosis market.
Reasons to buy
- Understand and capitalize by identifying products that are most likely to ensure a robust return- Stay ahead of the competition by understanding the changing competitive landscape for Osteoporosis- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential- Make more informed business decisions from insightful and in-depth analysis of drug performance- Obtain sales forecast for drugs from 2012-2022 in
ChinaTable of Contents
1 Table of Contents 41.1 List of Tables 71.2 List of Figures 82 Introduction 92.1 Catalyst 92.2 Related Reports 93 Disease Overview 123.1 Etiology and Pathophysiology 123.1.1 Etiology 123.1.2 Pathophysiology 153.1.3 Risk Factors 163.1.4 Quality of Life 163.2 Symptoms 174 Disease Management 184.1 Treatment Overview 184.1.1 Diagnosis and Referral 184.1.2 Treatment Guidelines 194.1.3 Disease Management 204.2
China 234.2.1 Diagnosis 234.2.2 Clinical Practice 245 Competitive Assessment 255.1 Overview 255.2 Strategic Competitor Assessment 255.3 Product Profiles –
Major Brands 295.3.1 Actonel (risedronate sodium) 295.3.2 Evista (raloxifene hydrochloride) 325.3.3 Reclast (zolendronic acid) 355.3.4 Forteo (teriparatide) 385.3.5 Prolia (denosumab) 425.3.6 Protelos (strontium ranelate) 455.3.7 Miacalcin and Fortical (calcitonin-salmon) 485.3.8 Viviant/Conbriza (bazedoxifene) 515.3.9 Recalbon/Bonoteo (minodronic acid hydrate) 54
5.3.10 Alendronate sodium 56
5.3.11 Ibandronate 586 Opportunity and Unmet Need 596.1 Overview 596.2 Unmet Needs 596.2.1 Disease Awareness and Early Diagnosis 596.2.2 Patient Compliance 606.2.3 Efficacy 616.2.4 Safety 616.2.5 Treatment Cost 626.2.6 Earlier Intervention 626.3 Unmet Needs Gap Analysis 636.4 Opportunity 1: Dual-Action Therapies 646.5 Opportunity 2: Osteoporosis Prevention Therapies 656.6 Opportunity 3: Dosing and Administration 657 Market Outlook 667.1
China 667.1.1 Forecast 667.1.2 Key Events 687.1.3 Drivers and Barriers 698 Appendix 708.1 Bibliography 708.2 Abbreviations 768.3 Methodology 798.4 Forecasting Methodology 798.4.1 Diagnosed Osteoporosis Patients 798.4.2 Percent Drug-Treated Patients 798.4.3 Drugs Included in Each Therapeutic Class 808.4.4 General Pricing Assumptions 808.4.5 Individual Drug Assumptions 808.4.6 Generic Erosion 848.5 Physicians and Specialists Included in this Study 858.5.1 About the Authors 868.5.2 Global Head of Healthcare 878.6 About GlobalData 888.7 Contact Us 888.8 Disclaimer 88
List of Tables
Table 1: Etiology of Primary Osteoporosis 12Table 2: Etiology of Secondary Osteoporosis 14Table 3: Symptoms of Osteoporosis 17Table 4: Diagnostic Tests for Osteoporosis 18Table 5: T-Score Ranges for Determination of
BMD 19Table 6: Treatment Guidelines for Osteoporosis 20Table 7: Most Prescribed Drugs for Osteoporosis by Therapeutic Class in the Global Markets, 2012 21Table 8: Leading Treatments for Osteoporosis, 2012 28Table 9: Product Profile – Actonel 30Table 10: Actonel SWOT Analysis, 2012 31Table 11: Product Profile – Evista 33Table 12: Evista SWOT Analysis, 2012 34Table 13: Product Profile – Reclast 36Table 14: Reclast SWOT Analysis, 2012 37Table 15: Product Profile – Forteo 39Table 16: Mean Percent Change from Baseline in BMD with Forteo vs. Placebo in Postmenopausal Women with Osteoporosis 40Table 17: Forteo SWOT Analysis, 2012 41Table 18: Product Profile – Prolia 42Table 19: Prolia SWOT Analysis, 2012 44Table 20: Product Profile – Protelos 45Table 21: Protelos SWOT Analysis, 2012 46Table 22: Product Profile – Miacalcin and Fortical Nasal Spray 49Table 23: Adverse Events with Miacalcin Nasal Spray 49Table 24: Miacalcin and Fortical Nasal Spray SWOT Analysis, 2012 50Table 25: Product Profile – Viviant/Conbriza 52Table 26: Viviant/Conbriza SWOT Analysis, 2012 53Table 27: Product Profile – Recalbon/Bonoteo 54Table 28: Recalbon/Bonoteo SWOT Analysis, 2012 55Table 29: Overall Unmet Needs – Current Level of Attainment 59Table 30: Clinical Unmet Needs – Gap Analysis, 2012 63Table 31: China Sales Forecasts ($m) for Osteoporosis, 2012-2022 67Table 32: Key Events Impacting Sales for Osteoporosis in the
China, 2012–2022 68Table 33: Osteoporosis Market – Drivers and Barriers in
China, 2012–2022 69Table 34: Number of High-Prescribing Physicians Surveyed 85
List of Figures
Figure 1: Sales for Osteoporosis Drugs in
China by Drug Class, 2012–2022 68
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