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PharmaPoint: Osteoporosis - India Drug Forecast And Market Analysis To 2022

NEW YORK, April 10, 2013 /PRNewswire/ -- announces that a new market research report is available in its catalogue:

PharmaPoint: Osteoporosis - India Drug Forecast and Market Analysis to 2022

PharmaPoint: Osteoporosis - India Drug Forecast and Market Analysis to 2022


GlobalData has released its new Country report, "PharmaPoint: Osteoporosis - India Drug Forecast and Market Analysis to 2022". Despite its maturity, the osteoporosis market is expected to undergo substantial change between 2012 and 2022. Most importantly, the 'gold-standard' bisphosphonates will lose patent protection by end-of-year 2013, flooding the marketplace with less expensive generic versions of these physician-preferred medications. Additionally, Eli Lilly's blockbuster Evista, the only available SERM in the US, will lose patent protection in 2014, flooding the market with yet more affordable generic options. Also during the forecast period covered by this report, osteoporosis drug development research will lead to the launches of a wave of novel anabolic drugs with greater efficacy and safety, causing a major market shift away from anti-resorptive drugs. The number of companies vying for patient share will shrink by as much as 50%, as established players exit the market or acquire smaller players. Lastly, the aging of the population in developed markets will result in a larger patient pool.

These changes in the osteoporosis market will be reflected in the slow growth during the forecast period, with the market growing from $6 billion to $8 billion in 2011 USD at a CAGR of 3%.

The recession will be caused by floods of generic products into the market. India has always had loose IP rights, requiring significant efficacy improvements in order for a drug to gain protection. However, as of 2012, India will start issuing compulsory licenses for Indian generics companies to violate IP and produce drugs prior to patent expiries. Therefore, GlobalData expects the Indian market to be dominated by generic products, and to lose significant value in the branded side of the drug market. For this reason, GlobalData did not project the pipeline products launching in the major markets because sales will likely be retarded by generic products.


- Overview of the Osteoporosis including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.- Detailed information on the key drugs in India including product description, safety and efficacy profiles as well as a SWOT analysis.- Sales forecast for the top drugs in India from 2012-2022.- Analysis of the impact of key events as well the drivers and restraints affecting India Osteoporosis market.

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return- Stay ahead of the competition by understanding the changing competitive landscape for Osteoporosis- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential- Make more informed business decisions from insightful and in-depth analysis of drug performance- Obtain sales forecast for drugs from 2012-2022 in India

Table of Contents

1 Table of Contents 41.1 List of Tables 71.2 List of Figures 82 Introduction 92.1 Catalyst 92.2 Related Reports 93 Disease Overview 123.1 Etiology and Pathophysiology 123.1.1 Etiology 123.1.2 Pathophysiology 153.1.3 Risk Factors 163.1.4 Quality of Life 163.2 Symptoms 174 Disease Management 184.1 Treatment Overview 184.1.1 Diagnosis and Referral 184.1.2 Treatment Guidelines 194.1.3 Disease Management 214.2 India 244.2.1 Diagnosis 244.2.2 Clinical Practice 245 Competitive Assessment 255.1 Overview 255.2 Strategic Competitor Assessment 255.3 Product Profiles – Major Brands 295.3.1 Actonel (risedronate sodium) 295.3.2 Evista (raloxifene hydrochloride) 325.3.3 Reclast (zolendronic acid) 365.3.4 Forteo (teriparatide) 395.3.5 Prolia (denosumab) 435.3.6 Protelos (strontium ranelate) 465.3.7 Miacalcin and Fortical (calcitonin-salmon) 495.3.8 Viviant/Conbriza (bazedoxifene) 535.3.9 Recalbon/Bonoteo (minodronic acid hydrate) 56 5.3.10 Alendronate sodium 58 5.3.11 Ibandronate 606 Opportunity and Unmet Need 616.1 Overview 616.2 Unmet Needs 626.2.1 Disease Awareness and Early Diagnosis 626.2.2 Patient Compliance 636.2.3 Efficacy 646.2.4 Safety 656.2.5 Treatment Cost 656.2.6 Earlier Intervention 666.3 Unmet Needs Gap Analysis 676.4 Opportunity 1: Dual-Action Therapies 696.5 Opportunity 2: Osteoporosis Prevention Therapies 696.6 Opportunity 3: Dosing and Administration 707 Pipeline Assessment 717.1 Overview 717.2 Promising Drugs in Clinical Development 727.2.1 Aprela (bazedoxifene and conjugated estrogens) 747.2.2 Romosozumab (AMG-785) 807.2.3 Odanacatib 867.2.4 BA-058 917.2.5 PTH(1-31)NH2 957.2.6 Ostora (recombinant salmon calcitonin) 1008 Market Outlook 1058.1 India 1058.1.1 Forecast 1058.1.2 Key Events 1078.1.3 Divers and Barriers 1089 Appendix 1109.1 Bibliography 1109.2 Abbreviations 1169.3 Methodology 1199.4 Forecasting Methodology 1199.4.1 Diagnosed Osteoporosis Patients 1199.4.2 Percent Drug-Treated Patients 1199.4.3 Drugs Included in Each Therapeutic Class 1209.4.4 General Pricing Assumptions 1209.4.5 Individual Drug Assumptions 1209.4.6 Generic Erosion 1259.4.7 Pricing of Pipeline Agents 1259.5 Physicians and Specialists Included in this Study 1269.5.1 About the Authors 1279.5.2 Global Head of Healthcare 1289.6 About GlobalData 1299.7 Contact Us 1299.8 Disclaimer 129

List of Tables

Table 1: Etiology of Primary Osteoporosis 12Table 2: Etiology of Secondary Osteoporosis 14Table 3: Symptoms of Osteoporosis 17Table 4: Diagnostic Tests for Osteoporosis 18Table 5: T-Score Ranges for Determination of BMD 19Table 6: Treatment Guidelines for Osteoporosis 20Table 7: Most Prescribed Drugs for Osteoporosis by Therapeutic Class in the Global Markets, 2012 22Table 8: Leading Treatments for Osteoporosis, 2012 28Table 9: Product Profile – Actonel 30Table 10: Actonel SWOT Analysis, 2012 31Table 11: Product Profile – Evista 33Table 12: Evista SWOT Analysis, 2012 34Table 13: Product Profile – Reclast 37Table 14: Reclast SWOT Analysis, 2012 38Table 15: Product Profile – Forteo 40Table 16: Mean Percent Change from Baseline in BMD with Forteo vs. Placebo in Postmenopausal Women with Osteoporosis 41Table 17: Forteo SWOT Analysis, 2012 42Table 18: Product Profile – Prolia 43Table 19: Prolia SWOT Analysis, 2012 45Table 20: Product Profile – Protelos 46Table 21: Protelos SWOT Analysis, 2012 47Table 22: Product Profile – Miacalcin and Fortical Nasal Spray 50Table 23: Adverse Events with Miacalcin Nasal Spray 51Table 24: Miacalcin and Fortical Nasal Spray SWOT Analysis, 2012 52Table 25: Product Profile – Viviant/Conbriza 53Table 26: Viviant/Conbriza SWOT Analysis, 2012 54Table 27: Product Profile – Recalbon/Bonoteo 56Table 28: Recalbon/Bonoteo SWOT Analysis, 2012 57Table 29: Overall Unmet Needs – Current Level of Attainment 61Table 30: Clinical Unmet Needs – Gap Analysis, 2012 67Table 31: Osteoporosis – Pipeline, 2012 72Table 32: Comparison of Therapeutic Classes in Development for Osteoporosis, 2012 72Table 33: Product Profile – Aprela 75Table 34: Aprela SWOT Analysis, 2012 79Table 35: Product Profile – Romosozumab 81Table 36: Romosozumab SWOT Analysis, 2012 85Table 37: Product Profile – Odanacatib 86Table 38: Odanacatib SWOT Analysis, 2012 90Table 39: Product Profile – BA-058 91Table 40: BA-058 SWOT Analysis, 2012 94Table 41: Product Profile – PTH(1-31)NH2 96Table 42: PTH(1-31)NH2 SWOT Analysis, 2012 98Table 43: Product Profile – Ostora 101Table 44: Ostora SWOT Analysis, 2012 103Table 45: India Sales Forecasts ($m) for Osteoporosis, 2012-2022 106Table 46: Key Events Impacting Sales for Osteoporosis in India, 2012–2022 107Table 47: Osteoporosis Market – Drivers and Barriers in India, 2012–2022 108Table 48: Number of High-Prescribing Physicians Surveyed 126

List of Figures

Figure 1: Company Portfolio Gap Analysis in Osteoporosis, 2012–2022 73Figure 2: Sales for Osteoporosis Drugs in India by Drug Class, 2012–2022 107

To order this report: Drug_and_Medication Industry: PharmaPoint: Osteoporosis - India Drug Forecast and Market Analysis to 2022

__________________________Contact Clare: US:(339) 368 6001 Intl:+1 339 368 6001

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