Cancers are generally believed to be derived from single cells that are genetically mutated, resulting in many divisions resulting in an expanding tumor that eventually spreads to local and distant organs. Cancer deaths usually are due to this metastasis affecting the new organs invaded. The initiating cells are often referred to as cancer stem cells. How these turn into heterogeneous populations of cancer cells within the original tumor and even in the metastases is the subject of intense recent research, which has also focused on the tumor's microenvironment and how cancer cells interact with their neighboring supportive cells.In a separate poster presentation at the same AACR Annual Meeting, the Company reported that genes of human cancer jump into adjacent normal cells by fusion of both cells. This study was done in collaboration with researchers from the Garden State Cancer Center, Center for Molecular Medicine and Immunology in Morris Plains, NJ, and the Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, in Bethesda, MD.
Immunomedics Creates Novel Antibody-Cytokine Conjugates For Cancer Therapy
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