TN currently affects approximately 50,000 people in the USA alone. The majority of people affected are over 50 years of age, however many cases have been reported in young adults. TN is more prevalent in women than men, and for most sufferers, the condition is progressive and worsens over time. TN is commonly misdiagnosed and to date there is no guaranteed cure for the condition. Current therapies are centred on sodium channel blockers such as carbamazepine or oxcarbazepine as first-line treatments. However, these agents although providing relief, are often poorly tolerated, and require lengthy dose escalation, resulting in sub-optimal efficacy.Clive Dix, Chief Executive Officer of Convergence Pharmaceuticals, added: "These interim data are very encouraging. Based on its preclinical and clinical profile, CNV1014802 offers the potential as an effective treatment for neuropathic pain, with a potentially better tolerability profile and wider therapeutic index than currently available treatments. We look forward to reporting full clinical results by the end of 2013."
Convergence Pharmaceuticals Announces Successful Interim Data From Ground-Breaking Phase II Trigeminal Neuralgia Study
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