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Prothena Announces Appointments Of Chief Medical Officer And Chief Financial Officer

About Prothena

Prothena Corporation plc (Nasdaq:PRTA) is a biotechnology company focused on the discovery and development of novel antibodies for the potential treatment of a broad range of diseases that involve protein misfolding or cell adhesion, particularly on the discovery and development of potential therapeutic monoclonal antibodies directed specifically to disease-causing proteins. These potential therapies have a broad range of indications, including AL and AA forms of amyloidosis, Parkinson's disease and related synucleinopathies, and novel cell adhesion targets involved in inflammatory disease and metastatic cancers. For more information, please visit www.prothena.com .

CONTACT: Investors:  
         Tran Nguyen
         650-837-8535, IR@prothena.com

         Media:  
         Anita Kawatra
         646-256-5116, anita.kawatra@prothena.com

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