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Therapeutic Drug Monitoring Markets

Table 10.5: Top-Selling Pharmaceutical Products by Bayer Healthcare

Pharmaceuticals 161

Table 10.6: Selected Bayer Products undergoing Registration 161

Table 10.7: Bayer -Top Selling Pharmaceutical Products by Sales, 2010-2011 162

Table 10.8: Life Science Product Portfolio – BioRad 163

Table 10.9: Customer Profile of BioRad 163

Table 10.10: Panel of BioRads Life Science Industry Competitors 163

Table 10.11: Panel of BioRads Clinical Diagnostic Industry Competitors 164

Table App 1.1: Variables that Contribute to Therapeutic Drug Monitoring Analysis

166

Table App 1.2: Common Drug Administration Routes 168

Table App 1.3: CYP Enzyme Metabolism of Clinically Relevant Therapeutic Agents

170

Table App 1.4: Major Sources of Pharmacokinetic Variability 170

Table App 1.5: Common Drug Groups involved in Therapeutic Drug Monitoring 172

Table App 1.6: Interpretative Criteria for a number of common drugs during

Therapeutic Drug Monitoring 173

INDEX OF FIGURES

Figure 2.1: Pharmacokinetics and TDM Relationship 18

Figure 2.2: Process for Reaching Dosage Decisions with Therapeutic Drug

Monitoring 19

Figure 2.3: Individualized Drug Treatment using Therapeutic Drug Monitoring 19

Figure 2.4: Pharmacokinetics and Pharmacodynamics Contribute to Variability in

the Relationship Between Therapeutic Dose and Effect 20

Figure 2.5: Concept of Therapeutic Range 20

Figure 2.6: Antiretroviral Coverage in Low and Middle Income Countries 24

Figure 2.7: Scenarios for Incremental Expansion of Antiretroviral Provision to

Treat and Prevent HIV 25

Figure 3.1: Number of Depression Sufferers in the U.S. 2005-2010 36

Figure 3.2: The Requirement for Immunosuppressant Drug Monitoring 42

Figure 3.3 Global Summary of the AIDS Epidemic 44

Figure 3.4: Number of People receiving Antiretroviral Therapy 44

Figure 4.1: Global Revenue of Therapeutic Drug Testing Market Forecast,

2009-2017 49

Figure 4.2 Geographic Market Share of the Therapeutic Drug Test Market 50

Figure 4.3: Global Market Share Analysis for Therapeutic Drug Testing (2012) 53

Figure 4.4: U.S. Market Share Analysis – Therapeutic Drug Testing (2012) 54

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