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Piramal Imaging Announces The Acceptance For Review Of [18F] Florbetaben By The FDA And EMA For The Visual Detection Of Beta-amyloid In Alzheimer's Disease

About florbetaben

[ 18F] florbetaben is an 18F-labeled tracer for use in positron emission tomography (PET) which specifically binds to beta-amyloid deposits in the brain, a key pathological hallmark in Alzheimer's disease. A Phase III trial presented for the first time at the annual meeting of the American Academy of Neurology in 2012 showed that PET imaging with [ 18F] florbetaben detects beta-amyloid in the brains of living subjects. The visual assessment procedure proposed for routine clinical practice demonstrated 100% sensitivity and 92% specificity.

About Alzheimer's disease

Alzheimer's disease is a progressive neurodegenerative disease which primarily affects people over the age of 60 and is the most common cause of dementia. In 2009 estimates suggested that more than 36 million people worldwide were suffering from Alzheimer's. This figure could exceed 115 million by 2050. At present there is no cure for the disease, although treatments which may help with certain symptoms, combined with the right services and support, can improve the quality of life for the millions of people living with Alzheimer's.

About Piramal Enterprises Ltd.

Piramal Enterprises is one of India's largest diversified companies with operations in pharmaceuticals, financial services and information management. Piramal Enterprises generated consolidated revenues of $500 million in the 2012 financial year. In pharmaceuticals field, Piramal Enterprises is one of the leading custom manufacturing players in the world and operates in the global critical-care segment with a portfolio of inhalation and injectable anesthetics. Its OTC business is ranked number 7 in India. PEL is also involved in drug discovery & research and has strong pipeline of development products. In the financial services field, PEL has a real-estate-focused PE fund called Indiareit, and an NBFC that focuses on lending to the real-estate and education sector. Recently, PEL also entered the global information-management industry by acquiring the US-based company Decision Resources Group. PEL acquired the global rights to a molecular-imaging research and development portfolio from Bayer AG. The portfolio includes the rights to [ 18F] florbetaben, a highly specialized molecule used in PET imaging to detect beta-amyloid in the brain, a widely recognized marker for Alzheimer's disease.

About Piramal Imaging SA

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