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VX-787 Showed Significant Antiviral Activity And Reduced The Severity And Duration Of Influenza Symptoms In Phase 2 Challenge Study

Vertex scientists and our collaborators are working on new medicines to cure or significantly advance the treatment of hepatitis C, cystic fibrosis, rheumatoid arthritis and other life-threatening diseases.

Founded more than 20 years ago in Cambridge, Mass., we now have ongoing worldwide research programs and sites in the U.S., U.K. and Canada. Today, Vertex has more than 2,000 employees around the world, and for three years in a row, Science magazine has named Vertex one of its Top Employers in the life sciences.

Special Note Regarding Forward-Looking Statements

This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, including, without limitation, Dr. Wright’s statements in the second paragraph of this press release and the statement regarding Vertex exploring collaborative opportunities to support further development of VX-787. While the company believes the forward-looking statements contained in this press release are accurate, there are a number of factors that could cause actual events or results to differ materially from those indicated by such forward-looking statements. Those risks and uncertainties include, among other things, the risks listed under Risk Factors in Vertex's annual report and quarterly reports filed with the Securities and Exchange Commission and available through Vertex's website at www.vrtx.com. Vertex disclaims any obligation to update the information contained in this press release as new information becomes available.

VRTX-GEN

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i Centers for Disease Control and Prevention. HIV in the United States: At a Glance. CDC Web site: http://www.cdc.gov/hiv/resources/factsheets/us.htm. Accessed February 28, 2013.

ii Centers for Disease Control and Prevention. Key Facts about Influenza (Flu) & Flu Vaccine. CDC Web site: www.cdc.gov/flu/keyfacts.htm. Accessed February 28, 2013.

iii Centers for Disease Control and Prevention. Influenza (Flu) Viruses. CDC Web site: http://www.cdc.gov/flu/about/viruses/index.htm. Accessed February 28, 2013.

iv Centers for Disease Control and Prevention. Key Facts about Influenza (Flu) & Flu Vaccine. CDC Web site: www.cdc.gov/flu/keyfacts.htm. Accessed February 28, 2013.

v Centers for Disease Control and Prevention. Season Influenza. CDC Web site: http://www.cdc.gov/flu/about/qa/disease.htm. Accessed February 28, 2013.

vi Centers for Disease Control and Prevention. Adult Immunization. CDC Web site: http://www.cdc.gov/workplacehealthpromotion/evaluation/topics/immunization.html. Accessed February 28, 2013.

vii Centers for Disease Control and Prevention. What you should know about flu antiviral drugs. CDC Web site: http://www.cdc.gov/flu/antivirals/whatyoushould.htm. Accessed February 28, 2013.
 

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