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Bio-Reference Laboratories, Inc. Will Offer Non-Invasive Prenatal Testing (NIPT) From Natera

ELMWOOD PARK, N.J., Feb. 27, 2013 (GLOBE NEWSWIRE) -- Bio-Reference Laboratories, Inc. (Nasdaq:BRLI) announced today that the Company and Natera have entered into a definitive agreement to commercialize the Panorama™ non-invasive prenatal screening test developed by Natera. The Panorama test will be sold by the GenPath business unit of Bioreference.

Panorama is a simple blood test that uses cutting-edge genotyping and sequencing technologies to identify chromosomal aneuploidies such as trisomies 13, 18, 21, and certain sex-chromosome abnormalities. According to the proceedings of the recent Society of Maternal Fetal Medicine conference held in San Francisco, non-invasive prenatal tests (NIPT) can reduce fetal loss by up to 91% while detecting the same amount of aneuploidies 13, 18, 21 by avoiding invasive Amniocentesis and chorionic villi sampling procedures. Panorama can be used starting 9th week of pregnancy.

Marc D. Grodman, MD, CEO of BRLI, commented: "With the recent guidelines published on non-invasive prenatal screening by ACOG, it is clear that this is a beneficial service to women and their clinicians while facing high-risk pregnancies. We are pleased to be able to offer Panorama as part of our full-service prenatal offering."

Added Matthew Rabinowitz, Ph.D., chief executive officer of Natera, "Our sophisticated technology has demonstrated that Panorama is clearly best in class, with a sensitivity and specificity unparalleled by others, and by combining forces with GenPath we are able to provide access to the test to the broadest patient population possible. In addition, the test is offered with a generous patient assistance program that enables Panorama to be available to all pregnant women, regardless of income level."

In clinical validation studies, Panorama demonstrated a sensitivity of greater than 99% when detecting common chromosomal abnormalities such as trisomy 21, trisomy 18 and trisomy 13; and 92% when detecting monosomy X. In addition, Panorama demonstrated a specificity of 100% with no false positives for all the syndromes tested. The test uses fetal cell-free DNA found in maternal blood and works as early as nine weeks gestation. Panorama's clinical validation data was presented live at the annual Society of Maternal Fetal Medicine Meeting on Feb. 15, 2013.

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