Results from this study will be submitted for presentation at upcoming scientific congresses and for publication in a peer-reviewed medical journal.
Lyrica is currently approved for various indications in 120 countries and regions globally.
In the U.S., Lyrica has been approved by the Food and Drug Administration for five indications. Lyrica was initially approved for partial onset seizures in adults with epilepsy who take one or more drugs for seizures. In 2007, Lyrica became the first FDA-approved treatment for the management of fibromyalgia. Other indications include neuropathic pain associated with diabetic peripheral neuropathy, post-herpetic neuralgia (pain after shingles) and the management of neuropathic pain associated with spinal cord injury (for which Lyrica became the first FDA- approved treatment in 2012). Lyrica’s ongoing clinical development program is focused on the significant unmet needs of patients with certain chronic pain conditions.
In the European Union, Lyrica is approved for four indications: peripheral and central neuropathic pain, generalized anxiety disorder in adults, and partial seizures with or without secondary generalization in adults with epilepsy.
In Japan, Lyrica is the only treatment approved for all three of the following indications: post-herpetic neuralgia, neuropathic pain and pain associated with fibromyalgia.
Antiepileptic drugs (AEDs), including Lyrica, increase the risk of suicidal thoughts or behavior in patients taking AEDs for any indication. There have been post-marketing reports of angioedema and hypersensitivity with Lyrica. Treatment with Lyrica may cause dizziness, somnolence, dry mouth, edema and blurred vision. Other most common adverse reactions include weight gain, constipation, euphoric mood, balance disorder, increased appetite and thinking abnormal (primarily difficulty with concentration/attention).
For Lyrica prescribing information in the United States visit
, in the European Union visit
and in Japan visit
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