To confirm and extend the initial findings, the team altered genes tied to NAD + production. The resulting shift again showed that higher NADH levels meant more aggressive tumors, while increased NAD + had the opposite effect.The next logical step was to find a simple way to enhance the critical NAD + level therapeutically. So the team explored what would happen if mice with breast cancer were fed water spiked with nicotinamide, a precursor for NAD + production. The scientists found cancer development was dramatically slowed down, and the mice lived longer
Scripps Research Institute Scientists Find Promising New Approach To Preventing Progression Of Breast Cancer
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