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NiGen BioTech's™ "The HCG Solution" Flying Off The Shelf At Walmart After Dr. Oz Show

In this second randomized, double-blind, placebo-controlled study, published in 2008,( J. E. Oben, et al., 2008) 48 obese and overweight subjects were randomly divided into two equal groups (n=24). No major changes in diet or exercise were suggested to the volunteers. The groups received either the same key extract found in The HCG Solution or a placebo twice daily before meals with 8-10 ounces of water. The capsules were identical in shape, color, and appearance, and neither the participants nor the researchers knew which treatment was administered. During the 10-week study period, subjects were evaluated for body weight, percent body fat, and waist circumference. Body weight and percent body fat were measured using a Tanita™ BC-418 Segmental Body Composition Analyzer/Scale that uses a bio-electrical impedance method for body composition analysis. Waist circumference was measured by soft, non-stretchable plastic tape on the narrowest and the widest parts of the trunk, and the values were averaged.

Of important note, some of the waist circumference values from the original publication ( J. E. Oben, et al., 2008) raised questions. Indeed, it was verified by the study author J. Oben that a different technician had carried out select waist measurements that were likely taken at a point lower than the navel, as had been the case for the prior measurements from the previous technician. NiGen BioTech therefore acquired the raw data from the study and excluded measurements from the study volunteers that were conducted by this alternative technician. This led to the removal of one volunteer's data from the placebo group and removal of 6 volunteers' data from The HCG Solution extract group.

After 8 weeks of treatment, the group taking the same key extract found in The HCG Solution had lost a significant 16.3 pounds compared to baseline (p<0.05), which increased to 19.4 pounds by week 10 (p<0.01). These results were also significant compared to placebo. In contrast, no weight changes were significant for the placebo group for the duration of the study.

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