This Day On The Street
Continue to site
ADVERTISEMENT
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here

Covidien Completes Enrollment In The DEFINITIVE AR Study

Covidien (NYSE:COV), a leading global provider of healthcare products, today announced the completion of enrollment in its DEFINITIVE AR (Anti-Restenosis) study. As the third study in the DEFINITIVE trial series, this randomized pilot is designed to address the challenge of preventing restenosis (re-narrowing of a blood vessel following treatment), a common occurrence in patients with peripheral artery disease (PAD).

According to the American Heart Association, approximately eight million people in the U.S. suffer from PAD. 1 PAD affects blood vessels throughout the body. When the vessels become clogged with plaque, blood flow slows or stops. If left untreated in the legs or feet, for example, this condition can lead to severe pain when walking, gangrene and even amputation.

The DEFINITIVE AR study is designed to evaluate the effect of treating a diseased vessel with a combination therapy that begins with directional atherectomy to remove plaque build-up, followed by the use of a drug-coated balloon that releases anti-proliferative medication to inhibit restenosis. As shown in the DEFINITIVE LE study, 2 directional atherectomy is effective in treating PAD without leaving a permanent implant behind. While the use of drug-coated balloons to treat PAD has demonstrated reduced vessel narrowing, there has been limited clinical study of the effectiveness of this treatment in calcified lesions. Using a directional atherectomy device to remove plaque build-up beforehand may increase how well drug-coated balloons work by improving the uniformity of drug delivery and thereby extending the amount of time the treated vessel stays open and reducing the need for subsequent treatments.

“Covidien is committed to building upon the growing body of clinical evidence for the use of directional atherectomy in the treatment of complex PAD,” said Mark A. Turco, MD, Chief Medical Officer, Vascular Therapies, Covidien. “We are eager to see the results of DEFINITIVE AR and to understand if this combination therapy of debulking followed by anti-restenotic therapy could lead to improved drug delivery and improved patient outcomes.”

1 of 3

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Only $9.95
14-Days Free
Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Real Money

More than 30 investing pros with skin in the game give you actionable insight and investment ideas.

Product Features:
  • Access to Jim Cramer's daily blog
  • Intraday commentary and news
  • Real-time trading forums
Only $49.95
14-Days Free
14-Days Free
SYM TRADE IT LAST %CHG
AAPL $93.74 0.00%
FB $117.58 0.00%
GOOG $693.01 0.00%
TSLA $240.76 0.00%
YHOO $36.60 0.00%

Markets

Chart of I:DJI
DOW 17,773.64 -57.12 -0.32%
S&P 500 2,065.30 -10.51 -0.51%
NASDAQ 4,775.3580 -29.9330 -0.62%

Free Reports

Top Rated Stocks Top Rated Funds Top Rated ETFs