- 2001: The FDA approved NuvaRing—which is marketed as a simpler and healthier alternative to a daily birth control pill—for use in the U.S.
- 2007: Schering-Plough purchases Organon for $14.4 billion.
- Beginning in May 2007: Complaints are filed in various jurisdictions asserting claims over the marketing and sale of NuvaRing .
- November 2009: Schering Plough completes its $4.1 billion merger with Merck.
- 2009: The British Medical Journal publishes two studies finding that women taking third- and fourth-generation progestins are almost twice as likely to develop blood clots as those taking second-generation oral contraceptives. First-generation birth control pills, developed in the 1960s, contained high levels of estrogen and carried a nine-fold increased risk of blood clots. Second-generation pills, developed in the 1970s, dramatically decreased blood-clot risks by combining lower doses of estrogen with the synthetic hormone progestin. NuvaRing contains a third-generation progestin, etonogestrel, which was developed to better control side effects like facial hair and acne.
- 2010: More than 5.5 million NuvaRing prescriptions are written in the U.S. NuvaRing generates $559 million in international sales.
- October 2011: An FDA-funded study finds that of 800,000 American women using some form of birth control between 2001 and 2008, NuvaRing users had a 56 percent increased risk of deep vein thrombosis and pulmonary embolism over women using second-generation birth control pills.
- May 2012: A Danish study published in the British Medical Journal reports that NuvaRing users had a 6.5 times higher risk of developing a serious blood clot compared to women who did not use any form of hormonal birth control; and a 90 percent higher risk of experiencing a dangerous blood clot than women taking combined oral contraceptives containing older forms of female hormones.
- 2012: NuvaRing's product information pamphlet claims that other studies have not shown any increased risk of blood clots in NuvaRing users over second-generation users.
- Through the middle of 2012, the FDA receives 4,974 Adverse Event reports from NuvaRing users.
- Today: Approximately 1.5 million women worldwide currently use NuvaRing which has not been recalled from the U.S. market.
Postponement Of NuvaRing Litigation Opens Door For New Plaintiffs; RD Legal Funding Offers NuvaRing Plaintiffs And Attorneys Post-Settlement Financing
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