This Day On The Street
Continue to site right-arrow
ADVERTISEMENT
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
Stocks Under $10 with 50-100% upside potential - 14 days FREE!

Diabetes, Metabolic Syndrome And Cardiovascular Disease

Table 3.13: Death Rate from Cardiovascular Diseases by Country, 2008 43

Table 3.14: Percentage of Adults Smokers by Country, 2008 47

Table 3.15: Selected Potential Patent Expirations of Cardiac Care Drugs, 2012-2013 48

Table 3.16: Worldwide Market for Cardiac Care Therapeutics, 2007-2014 49

Table 4.1: Global R&D Spending in the Pharmaceutical Industry, 2008-2012 56

Table 4.2: Pharmaceutical Companies Ranked by Total R&D Expenditures, 2011 56

Table 4.3: Leading Therapy Classes for R&D, 2012 57

Table 4.4: Global Pharmaceutical Sales by Region and Country, 2010 and 2015, and CAGR 2006-2010 and 2011-2015 58

Table 4.5: World Pharmaceutical Sales Share by Region, 2010 59

Table 4.6: Top Ten Global Pharmaceutical Companies by Global Sales, 2011 59

Table 4.7: Leading Ten Therapeutic Classes by U.S. Sales, 2006-2011 60

Table 4.8: Top Ten Therapeutic Classes by U.S. Dispensed Prescriptions, 2006-2011 60

Table 4.9: Leading Therapy Classes by Global Pharmaceutical Sales, 2015, and CAGR 2011-2015 61

Table 4.10: Top Selling Drugs in the U.S., 2010 61

Table 4.11: Worldwide Anti-Diabetes Drug Market, 2008-2016 63

Table 4.12: Oral Anti-Diabetic Therapy Major World Markets, 2010 63

Table 4.13: The Leading Five Anti-Diabetics by Sales, 2011 65

Table 4.14: American College of Physicians 2012 Practical Guideline for the Use of Anti-Diabetes Drugs for Type 2 Diabetes 66

Table 4.15: Summary of Glucose-Lowering Interventions as Monotherapy 70

Table 5.1: Classes of Non-Insulin Hypoglycemic Agents 73

Table 5.2: Non-Insulin Hypoglycemic Drugs Used to Treat Type 2 Diabetes, 2012 75

Table 5.3: Relative Efficacy of Diabetes Drugs 75

Table 5.4: Average Dose and Cost Comparison of Oral Hypoglycemic Agents 76

Table 5.5: Fixed-Dose Oral Anti-Diabetes Drug Combinations 88

Table 5.6: Delivery Method of Non-Insulin Anti-Diabetes Drugs in the Pipeline, 2011 93

Table 5.7: GLP-1 Agonist Pipeline: Selected Drugs in Development that Target GLP-1 94

Table 5.8: DPP-IV Inhibitor Pipeline 95

Table 5.9: Summary of Emerging Non-Insulin Anti-Diabetes Drug Categories 97

7 of 9

Select the service that is right for you!

COMPARE ALL SERVICES
Action Alerts PLUS
Try it NOW

Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
  • Weekly roundups
TheStreet Quant Ratings
Try it NOW
Only $49.95/yr

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
  • Upgrade/downgrade alerts
Stocks Under $10
Try it NOW

David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
  • Weekly roundups
Dividend Stock Advisor
Try it NOW

Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Alerts when market news affect the portfolio
  • Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
Real Money Pro
Try it NOW

All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.

Product Features:
  • Real Money + Doug Kass Plus 15 more Wall Street Pros
  • Intraday commentary & news
  • Ultra-actionable trading ideas
Options Profits
Try it NOW

Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • 100+ monthly options trading ideas
  • Actionable options commentary & news
  • Real-time trading community
  • Options TV
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!

Markets

DOW 17,787.20 +9.05 0.05%
S&P 500 2,067.13 +5.90 0.29%
NASDAQ 4,757.1030 +8.7070 0.18%

Brokerage Partners

Rates from Bankrate.com

  • Mortgage
  • Credit Cards
  • Auto

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs