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PharmaPoint: Rheumatoid Arthritis - United Kingdom Drug Forecast And Market Analysis Event-Driven Update

Table 2: Treatment Guidelines for Rheumatoid Arthritis 21

Table 3: Top Three Biologics Prescribed for Moderate-Severe Rheumatoid Arthritis by Market 23

Table 4: Treatment Guidelines for Rheumatoid Arthritis 27

Table 5: Product Profile - Enbrel 28

Table 6: 10 year Open-label Safety and Efficacy Trial of Enbrel: Efficacy Results at 11 years for Completers 29

Table 7: 10 year Open-label Safety and Efficacy Trial of Enbrel: Safety Results Overall 30

Table 8: Enbrel SWOT Analysis, 2012 32

Table 9: Product Profile - Humira 33

Table 10: Humira SWOT Analysis, 2012 35

Table 11: Product Profile - Remicade 37

Table 12: Remicade SWOT Analysis, 2012 39

Table 13: Product Profile - Simponi 41

Table 14: Simponi SWOT Analysis, 2012 43

Table 15: Product Profile - Cimzia 45

Table 16: Cimzia SWOT Analysis, 2012 47

Table 17: Product Profile - Orencia 48

Table 18: Orencia SWOT Analysis, 2012 50

Table 19: Product Profile - Actemra/RoActemra 52

Table 20: Actemra/RoActemra SWOT Analysis, 2012 54

Table 21: Product Profile - Rituxan 56

Table 22: Rituxan SWOT Analysis, 2012 58

Table 23: Product Profile - Methotrexate 60

Table 24: Methotrexate SWOT Analysis, 2012 61

Table 25: Summary of Minor Therapeutic Classes, 2012 62

Table 26: Overall Unmet Needs - Current Level of Attainment 63

Table 27: Clinical Unmet Needs - Gap Analysis, 2012 66

Table 28: Rheumatoid Arthritis - Phase Pipeline, 2012 68

Table 29: Comparison of Therapeutic Classes in Development for RA, 2012 69

Table 30: Product Profile - Tofacitinib 70

Table 31: Clinical Trial Locations by Country for Tofacitinib 71

Table 32: ORAL Standard ACR 20 Responses for Tofacitinib vs. Placebo vs. Humira at Month 6 71

Table 33: ORAL Step ACR 20, 50, 70 Responses for Tofacitinib vs. Placebo at Month Six 72

Table 34: Efficacy Issues Regarding Tofacitinib Determined by FDA Advisory Panel, May 2012 72

Table 35: Safety Issues Regarding Tofacitinib Determined by FDA Advisory Panel, May 2012 73

Table 36: Tofacitinib Clinical Trial Mortalities as of September 29, 2011 74

Table 37: Tofacitinib SWOT Analysis, 2012 75

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