Medgenics, Inc. (the “Company”) Issue Of Options And Restricted Shares To Directors And Officers

This announcement is being made pursuant to the London Stock Exchange’s AIM Rules for Companies admitted to trading on the AIM market.

Following the award of the Restricted Shares and grant of the Options to the non-executive Directors, the interests of the directors of the Company and their related parties and other significant shareholders in the Common Shares of which the Company is aware will be as follows:

Name		Common Shares		% of Issued Share Capital		Instrument		Number		Expiry Date		Exercise Price		Total interests		% of Issued Share Capital
Isaac Blech(Director) & related parties 1		1,652,471				Warrant		230,357		22/9/2015		$4.54
Total						Warrant		1,000,000		12/4/2016		$6.00
						Options		19,068		10/12/2020		$6.65
						Options		15,000		2/1/2022		$2.66
						Options		15,000		2/1/2023		$7.25
		7,000*
		1,659,471		13.4%				1,279,425						2,938,896		23.8%
Joel S. Kanter (Director) & related parties 2		1,207,332				Warrant		26,785		22/9/2015		$4.54
						Warrant		15,540		12/4/2016		$4.99
						Options		8,571		11/1/2021		$6.55
						Options		28,571		14/9/2020		$8.19
						Options		15,000		2/1/2022		$2.66
						Options		15,000		2/1/2023		$7.25
		7,000*
Total		1,214,332		9.8%		Options		109,377						1,323,709		10.7%
Andrew L. Pearlman (Director) & related parties 4		35,375				Warrant		35,922		31/3/2016		$0.0002
						Warrant		682,240		31/3/2016		$2.49
						Options		182,806		31/3/2016		$2.49
						Options		80,000		9/12/2021		$3.14
Total		35,375		0.3%				980,968						1,016,343		8.2%%
Beryl Steinberg		621,443				Warrant		21,885		12/4/2016		$4.99
Total		621,443		5.0%				21,885						643,328		5.2%
Chicago Investments, Inc. 3		637,008				Warrant		5,357		22/9/2015		$4.54
						Warrant		8,368		12/4/2016		$4.99
Total		637,008		5.2%				13,725						650,733		5.3%
Andrew Cader		788,950				Warrant		264,000		12/4/2016		$6.00
Total		788,950		6.4%				264,000						1,052,950		8.5%
CIBC Trust Company (Bahamas) Limited, as Trustee of T-555 3		349,386				Warrant		10,714		22/9/2015		$4.54
						Warrant		5,150		12/4/2016		$4.99
		349,386		2.8%				15,864						365,250		3.0%
Eugene A. Bauer (Director)		173,017				Options		28,571		14/9/2020		$8.19
		42,857*
Total		215,874		1.7%				28,571						244,445		2.0%
Stephen D. McMurray (Director)		79,835				Warrant		644		12/4/2016		$4.99
						Options		12,857		11/1/2021		$6.55
						Options		28,571		14/9/2020		$8.19
						Options		15,000		2/1/2022		$2.66
						Options		15,000		2/1/2023		$7.25
		7,000*
Total		86,835		0.7%				72,072						158,907		1.3%
Sol						Options		900,000		30-6-2017		$10.80
Barer (Director)						Options		15,000		2/1/2023		$7.25
		7,000*
Total		7,000		0.1%				915,000						922,000		7.5%
Alastair Clemow (Director)		7,000				Options		12,857		13/9/2020		$8.19
						Options		12,857		11/1/2021		$6.55
						Options		15,000		2/1/2022		$2.66
						Options		15,000		2/1/2023		$7.25
		7,000*
Total		14,000		0.1%				55,714						69,714		0.6%

• Restricted shares

Notes

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