- Program and Pipeline Highlights
- Submitted a pre-IND data package and subsequently completed a pre-IND meeting with the FDA on hepatitis B candidate ARC-520;
- Advanced ARC-520 into final IND-enabling steps, with IND filing expected in Q2 2013;
- Presented data on new DPC subcutaneous formulation showing 99% target gene knockdown in non-human primates without toxicity;
- Published studies in the journal Nucleic Acid Therapeutics demonstrating high levels of knockdown in non-human primates using cholesterol-conjugated siRNA, DPCs, and a novel co-injection strategy;
- Received additional patents on the DPC siRNA delivery system;
- Established a Clinical Advisory Board for hepatitis B including prominent hepatologist Dr. Robert G. Gish;
- Began dosing patients with anti-obesity treatment Adipotide ® in a phase 1 clinical trial;
- Completed patient dosing in a phase 1b trial of CALAA-01;
- Enrollment of a randomized phase 2 clinical study of partnered candidate CRLX101 (formerly IT-101) in non-small cell lung cancer completed by licensee Cerulean Pharma, with overall survival data expected in early 2013.
- Business Development Highlights
- Entered into a Collaboration and License Agreement with Shire for peptide-targeted therapeutics;
- Entered into an Evaluation Agreement with Merck for a monoclonal antibody candidate.
- Financial Highlights
- Strengthened the balance sheet through equity financings with gross proceeds of $10.5 million.
Arrowhead Reports Fiscal 2012 Fourth Quarter And Year-End Financial Results
Check Out Our Best Services for Investors
- $2.5+ million portfolio
- Large-cap and dividend focus
- Intraday trade alerts from Cramer
Access the tool that DOMINATES the Russell 2000 and the S&P 500.
- Buy, hold, or sell recommendations for over 4,300 stocks
- Unlimited research reports on your favorite stocks
- A custom stock screener
- Model portfolio
- Stocks trading below $10
- Intraday trade alerts
Every recommendation goes through 3 layers of intense scrutinyquantitative, fundamental and technical analysisto maximize profit potential and minimize risk.
Our options trading pros provide over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.