This Day On The Street
Continue to site
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here

MedImmune Announces Agreement With Progenics Pharmaceuticals To Develop Therapies Against Serious Bacterial Infections

About C. Difficile

C. difficile is an anaerobic bacterium that is mediated by toxins, which can damage the lining of the gut causing severe symptoms such as diarrhea and cramping, and prevent normal, beneficial bacteria (flora) in the gut from growing back.  An estimated 500,000 cases are diagnosed in the U.S. annually, resulting in more than20,000 deaths yearly.

The infection most often occurs in people who have been hospitalized, although up to 28 percent of cases are community-acquired through contaminated soil, water, pets, cattle, and foods.  Among people hospitalized, the incidence rate of the disease increases the longer a person stays in the hospital – from about 13 percent after a two-week stay to nearly 50 percent after four weeks.  The infection has an estimated 10 to 60 percent chance of recurring, depending on the patient's risk factors such as age, bacterial strain, and re-growth of normal, healthy bacteria in the gut.

Leadership in Infectious Diseases

MedImmune's historical roots are in infectious disease.  In 1998, it was the first company to launch a monoclonal antibody in the U.S. targeting an infectious disease (respiratory syncytial virus or RSV).

The company also is recognized as a leader in vaccine development, introducing the first influenza vaccine innovation in more than 60 years – intranasal delivery in 2003. MedImmune introduced another first earlier this year, the world's first four-strain flu vaccine, approved by the FDA in February and available in the U.S. in 2013.

MedImmune continues to explore how biologics can address the most hard-to-treat infectious diseases and help fulfill unmet needs among patients.  Research is ongoing in such diverse areas as antibacterials, respiratory viruses and novel vaccines. 

About MedImmune

MedImmune, the global biologics arm for AstraZeneca PLC, has approximately 3,500 employees worldwide and is headquartered in Gaithersburg, Maryland. For more information, visit MedImmune's website at

About Progenics

Progenics Pharmaceuticals, Inc., of Tarrytown, N.Y., is a biopharmaceutical company dedicated to developing innovative medicines to treat disease, with a focus on cancer and related conditions.  Progenics' pipeline candidates include PSMA ADC, a human monoclonal antibody-drug conjugate in phase 2 testing for treatment of prostate cancer, and preclinical stage novel phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of cancer.  Progenics has exclusively licensed development and commercialization rights for its opioid-induced constipation drug, Relistor, to Salix Pharmaceuticals, Ltd. for markets worldwide other than Japan, where Ono Pharmaceutical Co., Ltd. holds an exclusive license for the subcutaneous formulation.  Relistor (methylnaltrexone bromide) subcutaneous injection is a first-in-class treatment for opioid-induced constipation approved in more than 50 countries for patients with advanced illness.


2 of 3

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Only $9.95
14-Days Free
Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Real Money

More than 30 investing pros with skin in the game give you actionable insight and investment ideas.

Product Features:
  • Access to Jim Cramer's daily blog
  • Intraday commentary and news
  • Real-time trading forums
Only $49.95
14-Days Free
14-Days Free
AAPL $93.64 -0.11%
FB $118.57 0.84%
GOOG $698.21 0.75%
TSLA $241.80 0.43%
YHOO $36.53 -0.19%


Chart of I:DJI
DOW 17,891.16 +117.52 0.66%
S&P 500 2,081.43 +16.13 0.78%
NASDAQ 4,817.5940 +42.2360 0.88%

Free Reports

Top Rated Stocks Top Rated Funds Top Rated ETFs