Abstract # 2758 - Novel Imaging Modalities in Innovative Xenograft Mouse Models of T-Cell Lymphoma Confirm Marked Synergy of Romidepsin and PralatrexateUsing preclinical, in vivo xenograft tumor models, researchers at Stanford University and Columbia University demonstrated that FOLOTYN, when combined with another PTCL-approved therapy (Romidepsin), showed potential synergistic effects as measured by surface bioluminescence and ultrasound imaging. Ongoing pharmacokinetic and molecular studies are seeking to elucidate the mechanistic basis for the potential synergy in treating patients with PTCL, for whom prognosis still remains poor despite recent advances.
Spectrum Pharmaceuticals Highlights Promising ZEVALIN®, FOLOTYN® And Belinostat Clinical Data Presented At The 54th Annual Meeting Of The American Society Of Hematology
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