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Study Shows Positive Results For Prevena™ Incision Management System In Management Of Closed Surgical Incisions For Obese Patients

Kinetic Concepts, Inc. announced today that a new study published in The Journal of Thoracic and Cardiovascular Surgery showed that the Prevena™ Incision Management System used over closed incisions for the first six to seven days after a sternotomy demonstrated a significantly lower infection rate than conventional dressings in obese patients. Poor healing and infection following sternotomy are a significant problem in obese patients, associated with an increased risk of serious illness and death. Prolonged hospital stays and follow-up procedures can also increase the cost of care.

“This study showed that use of the Prevena™ System lead to a statistically significant reduction in infection rates of obese patients following median sternotomy,” said Prof. Onnen Grauhan, Senior Physician, Deutsches Herzzentrum Berlin, Germany. “Prevention of surgical site infections following cardiac surgery is much more cost effective than intervention, and the use of negative pressure over closed incisions may provide an answer for surgeons and healthcare providers wanting to avoid complications in this high-risk group of patients.”

The Deutsches Herzzentrum Berlin is an internationally renowned high-performance hospital for the treatment of cardiovascular and thoracic diseases, performing over 4500 major cardiovascular surgeries per year.

The prospective study compared the infection rates of 150 consecutive, obese patients who had received median sternotomy for cardiac surgery; 75 patients received negative pressure wound dressing treatments via the Prevena™ System (-125mmHg) for six to seven days, and the remaining 75 patients were given conventional wound dressings. After 90 days, only three (4 percent) of the 75 patients in the Prevena™ Therapy group showed infection, while 12 (16 percent) of the 75 patients in the conventional dressing group had infections at the incision site (p=0.0266).

“Results from this clinical study demonstrated a significant patient benefit in using Prevena™ Therapy on median sternal incisions,” said Ron Silverman, MD, chief medical officer, KCI. “It adds to the growing body of evidence that supports the use of Prevena™ Therapy over closed surgical incisions in patients that are considered at risk for a wound complication.”

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