This Day On The Street
Continue to site
This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here

Automated Online Sample Preparation Comes To Waters UltraPerformance Liquid Chromatography (UPLC) Platform

MILFORD, Mass., Nov. 20, 2012 /PRNewswire/ -- Waters Corporation (NYSE:WAT) announced today that its ACQUITY UPLC® System is now available with online solid phase extraction (SPE) technology from Spark Holland BV (Emmen, The Netherlands).  The Waters ® ACQUITY UPLC Online SPE Manager is based on a special version of the highly-popular Spark Holland online SPE technology, which Spark Holland is making available to Waters exclusively. The Waters ACQUITY UPLC Online SPE Manager is now available as an integrated Waters UPLC/MS system or as an upgrade to installed ACQUITY UPLC Systems under an agreement with Spark Holland. High-throughput analytical laboratories can now streamline sample preparation and analysis time and generate test results faster than before. The integrated system is sold and supported by Waters worldwide.

(Logo: )

"Combining our UPLC technology with Spark Holland's online SPE technology offers compelling benefits to high-throughput laboratories intent on producing the highest-quality test results, quickly and reproducibly for UPLC/MS analyses," said Ian King, Vice President, Separations Technologies, Waters Division. "Automating the process of sample preparation can help laboratories greatly improve turnaround times, reduce errors and the control costs." 

"Coupling online SPE to UPLC efficiently, while maintaining the unique benefit of disposable SPE cartridges, is a major technological challenge that performs best in a completely integrated fashion," said Rob van der Knaap, President, Spark Holland. "Integration of our online SPE technology with the ACQUITY UPLC System creates a superior platform for completely automated SPE-UPLC based analyses."

Leading laboratories use Spark Holland automated sample preparation devices to streamline sample preparation and analysis for routine, high throughput applications. Scientists employ online solid phase extraction when removing involatile salts, ion suppressing species and other interferences from samples prior to analysis. This reduces analysis time, reduces errors caused by manual SPE procedures, as well as provides a significant improvement in selectivity and concentrates analytes for better sensitivity. Covance Inc., one of the world's largest drug development services companies, employs automated online SPE and reports that it frequently allows quantification of even very large peptides down to the 10 pg/mL level in human plasma. 1

In 2007, Waters and Spark Holland announced the availability of the Waters Oasis® brand sorbent line for a newly-designed Spark Holland 800-series format tray for the Spark Holland ® Symbiosis™ and Prospekt-2™ systems. For the new system special UPLC ® cartridges are offered as well as novel applications. Spark Holland intends to expand its cartridge product line and applications portfolio continuously to serve clinical, pharmaceutical, food safety, and environmental control laboratories.

About Spark Holland (

Spark Holland has more than 30 years of history in HPLC and UHPLC instrument innovation, specializing in the field of autosampling and online solid phase extraction and, more recently, online dried blood spot analysis. Today, Spark Holland is a leading OEM supplier of front-end UHPLC and online solid phase extraction instruments, working according to ISO 13485 and, when required, delivering CE-IVD compliant  modules for use in clinical systems. Spark Holland is a privately held firm with operations based in Emmen, The Netherlands.

About Waters Corporation (

For over 50 years, Waters Corporation has created business advantages for laboratory-dependent organizations by delivering practical and sustainable innovation to enable significant advancements in such areas as healthcare delivery, environmental management, food safety, and water quality worldwide.

1 of 2

Check Out Our Best Services for Investors

Action Alerts PLUS

Portfolio Manager Jim Cramer and Director of Research Jack Mohr reveal their investment tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
Quant Ratings

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
Stocks Under $10

David Peltier uncovers low dollar stocks with serious upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
14-Days Free
Only $9.95
14-Days Free
Dividend Stock Advisor

David Peltier identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Updates with exact steps to take - BUY, HOLD, SELL
Trifecta Stocks

Every recommendation goes through 3 layers of intense scrutiny—quantitative, fundamental and technical analysis—to maximize profit potential and minimize risk.

Product Features:
  • Model Portfolio
  • Intra Day Trade alerts
  • Access to Quant Ratings
Real Money

More than 30 investing pros with skin in the game give you actionable insight and investment ideas.

Product Features:
  • Access to Jim Cramer's daily blog
  • Intraday commentary and news
  • Real-time trading forums
Only $49.95
14-Days Free
14-Days Free


Chart of I:DJI
DOW 16,955.91 +43.62 0.26%
S&P 500 1,995.83 +15.91 0.80%
NASDAQ 4,758.39 -32.7620 -0.68%

Free Reports

Top Rated Stocks Top Rated Funds Top Rated ETFs