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METALJET Extremely Bright X-ray Source (Photo: Business Wire)

At the 2012 triennial International Small-Angle Scattering Conference ( http://sas2012.com), Bruker launches the METALJET , a novel and extremely bright microfocus X-ray source for structural biology applications. The unique METALJET is now offered exclusively by Bruker as a source option for D8 VENTURE TM protein crystallography systems and for NANOSTAR TM Small Angle X-ray Scattering (SAXS) systems.

METALJET Extremely Bright X-ray Source (Photo: Business Wire)

METALJET Extremely Bright X-ray Source (Photo: Business Wire)

The METALJET source for Bruker structural biology systems was developed in collaboration with Excillum AB and Incoatec GmbH as the most intense home-lab microfocus X-ray source available today outside of synchrotron beamlines. This revolutionary new liquid metal source technology is well suited to meet the ever-increasing demands of modern structural biology, and particularly of protein crystallography and of small angle X-ray scattering.

Just like conventional rotating anode generators and microfocus sources, the METALJET uses the impact of electrons onto a metal target to generate X-rays. However, the solid anode of conventional generators is replaced by a high-speed jet of liquid metal that can accept a much higher power load. The result is an X-ray beam that is brighter than what is currently achievable with the most powerful laboratory X-ray sources.

The transmission and delivery of such a small X-ray beam also requires technical innovations in the design of X-ray optics, since a smaller X-ray source requires greater precision during the deposition process of the multilayers for X-ray mirrors. The new HELIOS MX TM X-ray optics, developed by Incoatec for the METALJET , transmits the X-rays to the crystal sample in a uniformly small diameter, greatly exceeding the intensity of traditional X-ray sources.

Despite this unparalleled analytical performance, the new METALJET source also features a cost of ownership that is very competitive with conventional rotating anode sources.

The unprecedented brightness of the new METALJET source will allow researchers to bring into the home lab many experiments that previously could only be accomplished at a synchrotron. The METALJET enables structural biologists to collect data on smaller, more weakly-diffracting crystals, improving home-lab productivity more than ever before.

Oscar Hemberg, PhD, the CEO of Excillum AB, said: “We are very proud that Excillum’s liquid-metal-jet-anode X-ray source technology now will be introduced to Bruker’s customers after two years of intense product development and thorough internal evaluations at Bruker.”

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