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ACADIA Pharmaceuticals Reports Third Quarter 2012 Financial Results

Research and development expenses increased to $4.4 million for the third quarter of 2012, including $157,000 in stock-based compensation, from $4.2 million for the third quarter of 2011, including $129,000 in stock-based compensation. This increase was primarily due to increased external clinical expenses associated with ACADIA’s Phase III program with pimavanserin.

General and administrative expenses totaled $1.5 million for the third quarter of 2012, including $331,000 in stock-based compensation, and were comparable to the third quarter of 2011.

Conference Call and Webcast Information

ACADIA management will review its third quarter financial results and development programs via conference call and webcast later today at 5:00 p.m. Eastern Time. The conference call may be accessed by dialing 866-203-3436 for participants in the U.S. or Canada and 617-213-8849 for international callers (reference passcode 61271381). A telephone replay of the conference call may be accessed through November 19, 2012 by dialing 888-286-8010 for callers in the U.S. or Canada and 617-801-6888 for international callers (reference passcode 76643395). The conference call also will be webcast live on ACADIA’s website,, under the investors section and will be archived there until November 19, 2012.

About ACADIA Pharmaceuticals

ACADIA is a biopharmaceutical company focused on innovative treatments that address unmet medical needs in neurological and related central nervous system disorders. ACADIA has a pipeline of product candidates led by pimavanserin, which is in Phase III development as a potential first-in-class treatment for Parkinson's disease psychosis. ACADIA also has clinical-stage programs for chronic pain and glaucoma in collaboration with Allergan, Inc. and two preclinical programs directed at Parkinson’s disease and other neurological disorders. All of ACADIA’s product candidates are small molecules that emanate from discoveries made using its proprietary drug discovery platform. ACADIA maintains a website at to which ACADIA regularly posts copies of its press releases as well as additional information and through which interested parties can subscribe to receive email alerts.

Forward-Looking Statements

Statements in this press release that are not strictly historical in nature are forward-looking statements. These statements include but are not limited to statements related to the progress and timing of ACADIA’s drug discovery and development programs, either alone or with a partner, including clinical trials and the results therefrom, the potential of and the benefits to be derived from product candidates, in each case including pimavanserin, including the timing of results of the -020 trial, the future growth of ACADIA, and the period during which ACADIA’s cash resources will be sufficient to fund its operations. These statements are only predictions based on current information and expectations and involve a number of risks and uncertainties. Actual events or results may differ materially from those projected in any of such statements due to various factors, including the risks and uncertainties inherent in drug discovery, development and commercialization, and collaborations with others, and the fact that past results of clinical trials may not be indicative of future trial results. For a discussion of these and other factors, please refer to ACADIA’s annual report on Form 10-K for the year ended December 31, 2011 as well as ACADIA’s subsequent filings with the Securities and Exchange Commission. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. This caution is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. All forward-looking statements are qualified in their entirety by this cautionary statement and ACADIA undertakes no obligation to revise or update this press release to reflect events or circumstances after the date hereof, except as required by law.



(in thousands, except per share amounts)

Three Months Ended September 30, Nine Months Ended September 30,
  2012           2011     2012           2011  
Collaborative revenues $ 3,478 $ 584 $ 4,527 $ 1,479
Operating expenses
Research and development (includes stock-based compensation of $157, $129, $450 and $383, respectively) 4,400 4,158 13,893 12,885

General and administrative (includes stock-based compensation of $331, $272, $929 and $807, respectively)
  1,485     1,519     4,701     6,132  
Total operating expenses   5,885     5,677     18,594     19,017  
Loss from operations (2,407 ) (5,093 ) (14,067 ) (17,538 )
Interest income, net   5     17     28     73  
Net loss $ (2,402 ) $ (5,076 ) $ (14,039 ) $ (17,465 )
Net loss per common share, basic and diluted $ (0.04 ) $ (0.10 ) $ (0.26 ) $ (0.34 )
Weighted average common shares outstanding, basic and diluted   53,911     52,800     53,262     51,963  



(in thousands)

September 30,

December 31,

Cash, cash equivalents and investment securities $ 23,058 $ 31,048
Prepaid expenses, receivables and other current assets   627   901
Total current assets 23,685 31,949
Property and equipment, net, and other assets   65   165
Total assets $ 23,750 $ 32,114
Liabilities and Stockholders’ Equity
Accounts payable, accrued expenses and other current liabilities $ 5,820 $ 5,496
Current portion of deferred revenue   266   669
Total current liabilities 6,086 6,165
Long-term portion of deferred revenue   -   2,587
Total liabilities 6,086 8,752
Stockholders’ equity   17,664   23,362
Total liabilities and stockholders’ equity $ 23,750 $ 32,114


The condensed consolidated balance sheet at December 31, 2011 has been derived from the audited financial statements at such date but does not include all of the information and footnotes required by accounting principles generally accepted in the United States for complete financial statements.

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