ArQule To Report Third Quarter 2012 Financial Results On November 1, 2012

ArQule, Inc. (NASDAQ: ARQL) today announced that it will report its financial results for the third quarter of 2012 on Thursday, November 1, 2012 at 7:00 a.m. eastern time. The Company will hold a conference call at 9:00 a.m. eastern time that day to discuss these results.

Conference Call and Webcast
Date:		Thursday, November 1, 2012
Time:		9:00 a.m., Eastern Time
Conference Call Numbers
Domestic (toll free):		[phone]
International:		[phone]
Webcast:		http://investors.arqule.com/events.cfm

A replay of the conference call will be available beginning on November 1, 2012 approximately two hours after the call’s completion for seven days and can be accessed by dialing toll-free [phone] and outside the U.S. [phone]. The confirmation code for archived calls is 53861797.

About ArQule

ArQule is a biotechnology company engaged in the research and development of next-generation, small-molecule cancer therapeutics. The Company’s targeted, broad-spectrum products and research programs are focused on key biological processes that are central to human cancers. ArQule’s lead product, in Phase 2 and Phase 3 clinical development, is tivantinib (ARQ 197), an oral, selective inhibitor of the c-MET receptor tyrosine kinase. The Company’s pipeline consists of ARQ 621, designed to inhibit the Eg5 kinesin motor protein, and ARQ 736, designed to inhibit the RAF kinases. ArQule’s current discovery efforts, which are based on the ArQule Kinase Inhibitor Platform (AKIP™), are focused on the identification of novel kinase inhibitors that are potent, selective and do not compete with ATP (adenosine triphosphate) for binding to the kinase.

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