The superior choice that arGEN-X brings to antibody discovery enables it to prioritise leads with best-in-class therapeutic properties, thereby increasing the probability of development success. Antibody leads generated from the SIMPLE Antibody™ platform have outstanding physicochemical properties and consistent manufacturability, enabling a seamless transition from discovery into development. arGEN-X has validated its technology on multiple diverse classes of target to date and has successfully delivered in its collaboration with Eli Lilly & Co. Early in 2012, arGEN-X announced a strategic alliance with Shire, focused on the discovery and development of monoclonal antibody therapeutics to treat rare diseases. In October 2012, arGEN-X granted a worldwide exclusive license to RuiYi (formerly Anaphore) to develop and commercialize ARGX-109, a novel anti-IL-6 SIMPLE Antibody™ discovered and developed by arGEN-X.
The SIMPLE Antibody™ platform is covered by broad patent claims, enjoys an independent, unencumbered patent position and is free of target gatekeeping restrictions.
In March 2012, arGEN-X obtained an exclusive global license to technology known as NHance™, to optimize the pharmacokinetic half-life of monoclonal antibodies and maximize their therapeutic utility.
SIMPLE stands for Superior Immunodiversity with Minimal Protein Lead Engineering.arGEN-X™, SIMPLE Antibody™ and NHance™ are deposited trademarks of arGEN-X BV. SOURCE arGEN-X