Elan’s net Tysabri ROW revenue is calculated as follows:
|Three Months Ended||Nine Months Ended|
|September 30||September 30|
|195.5||173.3||ROW in-market sales by Biogen Idec||580.9||555.3|
|(87.9)||(70.9)||ROW operating expenses incurred by the collaboration||(264.3)||(233.1)|
|107.6||102.4||ROW operating profit incurred by the collaboration||316.6||322.2|
|53.8||51.2||Elan’s 50% share of Tysabri ROW collaboration operating profit||158.3||161.1|
|28.1||24.7||Elan’s directly incurred costs||85.1||78.9|
|81.9||75.9||Net Tysabri ROW revenue||243.4||240.0|
Elan ceased distributing Azactam as of March 31, 2010, and Maxipime as of September 30, 2010. The revenue and adjustments for these products in 2011 and 2012 relates to adjustments to discounts and allowances associated with sales prior to the cessation of distribution.
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