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Abbott Announces Three-Year Long-Term Data Evaluating Efficacy With HUMIRA® (Adalimumab) For Patients With Moderately To Severely Active Ulcerative Colitis

Stocks in this article: ABT

About UCUC is an inflammatory bowel disease marked by inflammation in the rectum and colon, resulting in diarrhea, rectal bleeding and abdominal cramping.  Typically, people are diagnosed with UC in their mid-30s, though the disease can occur at any age.

The symptoms of UC tend to come and go, with varying periods of clinical stability punctuated by episodic flares of disease activity.  Severe flares of UC can necessitate hospitalization and can be life-threatening. Treatment may include medication and/or surgery.

About HUMIRAHUMIRA is used in adults to help get moderate to severe ulcerative colitis under control (induce remission) and keep it under control (sustain remission) when certain other medicines have not worked well enough.  It is not known if HUMIRA is effective in people who stopped responding to or could not tolerate anti-TNF medicines.

Globally, uses and prescribing information vary; please refer to the individual country label for complete information.

Important Safety InformationHUMIRA is a TNF blocker medicine that affects the immune system and can lower the ability to fight infections.   Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections.  People should be tested for TB before HUMIRA use and monitored for signs and symptoms of TB during therapy. People at risk of TB may be treated with medicine for TB.  Treatment with HUMIRA should not be started in a person with an active infection, unless approved by a doctor.  HUMIRA should be stopped if a person develops a serious infection.  People should tell their doctor if they live in or have been to a region where certain fungal infections are common, have had TB, hepatitis B, are prone to infections, or have symptoms such as fever, fatigue, cough, or sores.

For people taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase.  Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma.  This type of cancer often results in death. If using TNF blockers including HUMIRA, the chance of getting two types of skin cancer (basal cell and squamous cell) may increase.  These types are generally not life threatening if treated.

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