Exact Sciences Corp. (Nasdaq: EXAS) this afternoon presented a scientific poster at the International Frontiers in Cancer Prevention Research, a meeting of the American Association for Cancer Research. A copy of the poster, titled “An Optimized Molecular Stool Test for Colorectal Cancer Screening: Evaluation of an Automated Analytic Platform and Logistic Algorithm,” can be found at
The study that generated the data presented today included 1,003 patients at 36 study centers. Among the study population, there were 93 cases of colorectal cancer, 114 cases of advanced pre-cancers and 796 controls.
“We are very pleased with the performance of our noninvasive, stool DNA-based colorectal cancer screening test in this latest validation study,” said Kevin T. Conroy, president and chief executive of Exact Sciences. “At a nominal specificity of 90 percent, the test achieved sensitivity of 98 percent in the detection of cancer and 83 percent in the detection of high-grade dysplasia cases, the majority of which progress to cancer. The test demonstrated 57 percent sensitivity in the detection of advanced pre-cancers equal to or larger than 1 centimeter. The test’s sensitivity increased with the pre-cancers’ size, rising to 83 percent for pre-cancers larger than 3 centimeters. The study was conducted using the automation platform that will be used in the DeeP-C pivotal study and will be part of our FDA submission.”
About Exact Sciences Corp.
Exact Sciences Corp. is a molecular diagnostics company focused on colorectal cancer. The company has developed a proprietary, multi-target, stool-DNA colorectal cancer screening test that runs on an automated testing platform. It is conducting a clinical trial called the DeeP-C study that has enrolled more than 10,000 patients and includes both the test and the automation platform. Stool-based DNA technology is included in the colorectal cancer screening guidelines of the American Cancer Society and the U.S. Multi-Society Task Force on Colorectal Cancer. For more information, please visit the company’s website at
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