Results showed odanacatib significantly increased BMD compared to placeboIn the odanacatib group, BMD changes from baseline at 24 months were significantly different versus placebo at all three hip sites (+1.73%, +1.83%, +0.83% for the femoral neck, hip trochanter, and total hip, respectively, vs. -0.94%, -1.35%, -1.87% with placebo), and the lumbar spine (+2.28% vs. -0.30% change with placebo). At the distal forearm, BMD changes from baseline at 24 months were -0.92% and -1.14%. The difference versus placebo at the distal forearm (+0.22%) was not statistically significant.
Merck Researchers Present BMD Data From A Phase II Study Of Odanacatib, Merck’s Investigational Cat-K Inhibitor For Post-Menopausal Osteoporosis
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