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Hormone Therapy Has Many Favorable Effects In Newly Menopausal Women: Initial Findings Of The Kronos Early Estrogen Prevention Study (KEEPS)

About FundingThe core KEEPS was funded by the Phoenix-based Kronos Longevity Research Institute which is supported by the not-for-profit Aurora Foundation and carried out at nine U.S. academic medical centers (see below). The Cognitive and Affective Study is National Institutes of Health funded ancillary study of KEEPS that was coordinated by investigators based at the University of Wisconsin in Madison, WI.

About KLRIKLRI is a not-for-profit 501(c)(3) organization that conducts state-of-the-art clinical translational research on the prevention of age-related diseases and ways to increase longevity. Translational research is the critical link between findings from the basic research laboratory and corresponding improvements in clinical care. For more information on KEEPS, visit or call 1(866) 878-1221.

The nine KEEPS study centers

  • Kronos Longevity Research Institute (the Sponsor) (Dr. Mitch Harman, PI)
  • Albert Einstein College of Medicine/Montefiore Medical Center ( New York City; Drs. Nanette Santoro and Genevieve Neal-Perry, PIs)
  • Columbia University College of Physicians and Surgeons ( New York City, Dr. Rogerio Lobo, PI)
  • Harvard Medical School/Brigham and Women's Hospital ( Boston, Dr. JoAnn Manson, PI)
  • Mayo Clinic College of Medicine ( Rochester, MN, Dr. Virginia Miller, PI)
  • University of California, San Francisco/Center for Reproductive Health (Dr. Marcelle Cedars, PI)
  • University of Utah School of Medicine ( Salt Lake City, Drs. Eliot Brinton and Paul Hopkins, PIs)
  • University of Washington School of Medicine ( Seattle, Dr. George Merriam, PI)
  • Yale University School of Medicine ( New Haven, CT, Dr. Hugh Taylor, PI)

Evaluation of arterial imaging was coordinated by

  • Atherosclerosis Research Unit, Keck School of Medicine of USC (CIMT, Dr. Howard Hodis)
  • St. Johns Cardiovascular Research Center and the UCLA School of Medicine (CAC, Dr. Matthew Budoff)

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