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New Edition Of Definitive (Two-Volume) Resource In Stem Cells Released Today

Advanced Cell Technology, Inc. (“ACT”; OTCBB: ACTC), a leader in the field of regenerative medicine, announced today that its chief scientific officer, Robert Lanza, M.D. and Anthony Atala, M.D., W.H. Boyce Professor and Director of the Wake Forest Institute for Regenerative Medicine, have released the second edition of Handbook of Stem Cells (Academic Press/Elsevier), the widely-recognized definitive resource in the field of stem cells. It includes a Forward by Professor Sir Martin Evans, Ph.D., FRS, co-winner of the Nobel Prize for Physiology or Medicine in 2007. Sir Martin is credited with discovering embryonic stem cells and is considered one of the chief architects of the field of stem cell research. The two-volume set also includes contributions from dozens of stem cell pioneers, including James Thomson, Shinya Yamanaka, Doug Melton, Janet Rossant, and Robert Langer (a member of ACT’s board of directors), among others, as well as patient advocate Mary Tyler Moore.

Handbook of Stem Cells, Second Edition follows a very successful edition published in 2004. The first edition was the first comprehensive body of work dedicated entirely to the stem cell field. The two-volume set quickly became the most relevant textbook in the stem cell arena. Now, several years later, major advances have occurred, with entirely new classes of stem cells being described. The description of induced pluripotent cells in the last few years brought many more avenues of research and discovery. In 2012, the first paper reporting results of two patients treated with human embryonic stem cells was published by ACT and its collaborators. It might seem that we have waited too long to finally see pluripotent stem cells in the clinic. However, this has been accomplished with incredible speed when it is considered that hESCs were first isolated just 14 years ago. Handbook of Stem Cells integrates this exciting area, combining in two volumes the requisites for a general understanding of both adult and embryonic stem cells. Organized in two volumes, Pluripotent Stem Cells and Adult & Fetal Stem Cells, this work contains contributions from the world's experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system.

“The Handbook of Stem Cells, edited by Robert Lanza and colleagues, is an ambitious new text that achieves extraordinary completeness and inclusiveness,” wrote Steve Goldman of University of Rochester Medical Center in NATURE CELL BIOLOGY about the first edition. “[...] the editors have succeeded in putting together a reference that is broad enough in scope, but sufficiently detailed and rigorous, to be of real interest to both new and seasoned investigators in the field [...] In providing this treatise, which covers the history, biology, methods and applications of stem cells, the editors and authors have succeeded in establishing a conceptual framework and a common language for the field. In so doing, they have ensured that this two-volume set will serve as a benchmark reference in stem cell biology for years to come.”

Writing about the first edition in the Times Higher Education Supplement, Ian Wilmut added, “These books make an invaluable contribution to the education of researchers and clinicians both of the present day and of the future. They should be available in libraries of all biology and medical schools as well as those of companies and research institutions.”

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