Compressed carbon dioxide (CO 2), the primary mobile phase for convergence chromatography, offers numerous major advantages over liquid mobile phases or carrier gases that are used with LC and GC. For one, CO 2 alone, or in combination with a co-solvent, is a low viscosity mobile phase that achieves higher diffusion rates and enhanced mass transfer than HPLC liquids. For another, when compared to GC, CO 2 allows separations to occur at a much lower temperature.
For institutions and laboratories with sustainability goals to meet, CO
replaces toxic and volatile organic solvents that are very expensive to purchase and dispose.
For Prof. Shulaev, teaching the use of analytical instruments is another critical part of his work. "It's very important to train the next generation of scientists, especially in mass spectrometry, which is one of the big deficiencies now," he said. "We need to have a big pool of people who understand mass spectrometry and technology – and not just understand it in theory, but in practice."
With nearly 30 years of experience in metabolic biochemistry and plant and animal biology, Prof. Shulaev's research is at the cutting edge of a wide range of important scientific developments, including crop protection, cancer treatments and nutrition. Among his accomplishments, Prof. Shulaev is credited with helping to identify methyl salicylate as a new volatile plant hormone involved in plant immunity. He is also an adjunct professor in the Department of Cancer Biology at
Wake Forest University
School of Medicine. Prof. Shulaev has been an investigator on research projects totaling about
About Waters Centers of Innovation Program
Waters Centers of Innovation Program
recognizes and supports the efforts of scientists facilitating breakthroughs in health and life science research, food safety, environmental protection, sports medicine and many other areas.
Prof. Shulaev joins 18 other researchers and research centers recognized by Waters' Centers of Innovation Program. The others include
Professor Jeremy Nicholson
, Imperial College London;
Professor John Engen
Professor James Scrivens
University of Warwick
Professor David Cowan
Professor Arthur Moseley
Durham, North Carolina
Professor Julie Leary
University of California
– Davis; and
Professor Albert J. Fornace, Jr.
, Georgetown Lombardi Comprehensive Cancer
Professor Marcos Eberlin
, University of Campinas,
Professor Ganesh Anand
National University of Singapore
Dr. Konstantinos Petritis
, Translational Genomics Research Institute,
Dr. Joseph Dalluge
University of Minnesota
Prof. Sarah Trimpin
Wayne State University
Dr. Frank Gonzalez
, National Cancer Institute;
Dr. Devin Peterson
University of Minnesota
and Eric Lesselier,
University of Orleans
Professor Burt van Bavel
, Orebro University;
Professor Pauline Rudd
, National Institute for Bioprocessing Research and Training; and
Dr. Amit Kumar Mandal
, St. John's Research Institute,
These leading scientists, in partnership with Waters, are using liquid chromatography and mass spectrometry to help shape the future of scientific research and unlock the mysteries of science.