Compressed carbon dioxide (CO 2), the primary mobile phase for convergence chromatography, offers numerous major advantages over liquid mobile phases or carrier gases that are used with LC and GC. For one, CO 2 alone, or in combination with a co-solvent, is a low viscosity mobile phase that achieves higher diffusion rates and enhanced mass transfer than HPLC liquids. For another, when compared to GC, CO 2 allows separations to occur at a much lower temperature.
For institutions and laboratories with sustainability goals to meet, CO 2 replaces toxic and volatile organic solvents that are very expensive to purchase and dispose.
For Prof. Shulaev, teaching the use of analytical instruments is another critical part of his work. "It's very important to train the next generation of scientists, especially in mass spectrometry, which is one of the big deficiencies now," he said. "We need to have a big pool of people who understand mass spectrometry and technology – and not just understand it in theory, but in practice."
With nearly 30 years of experience in metabolic biochemistry and plant and animal biology, Prof. Shulaev's research is at the cutting edge of a wide range of important scientific developments, including crop protection, cancer treatments and nutrition. Among his accomplishments, Prof. Shulaev is credited with helping to identify methyl salicylate as a new volatile plant hormone involved in plant immunity. He is also an adjunct professor in the Department of Cancer Biology at Wake Forest University School of Medicine. Prof. Shulaev has been an investigator on research projects totaling about $9 million.About Waters Centers of Innovation Program Waters Centers of Innovation Program recognizes and supports the efforts of scientists facilitating breakthroughs in health and life science research, food safety, environmental protection, sports medicine and many other areas. Prof. Shulaev joins 18 other researchers and research centers recognized by Waters' Centers of Innovation Program. The others include Professor Jeremy Nicholson, Imperial College London; Professor John Engen, Northeastern University, Boston, Mass.; Professor James Scrivens, University of Warwick, Coventry, UK; Professor David Cowan of Kings College London; Professor Arthur Moseley of Duke University, Durham, North Carolina; Professor Julie Leary of the University of California – Davis; and Professor Albert J. Fornace, Jr., Georgetown Lombardi Comprehensive Cancer Center, Washington, D.C.; Professor Marcos Eberlin, University of Campinas, Brazil; Professor Ganesh Anand, National University of Singapore; Dr. Konstantinos Petritis, Translational Genomics Research Institute, Phoenix, Arizona; Dr. Joseph Dalluge, University of Minnesota; Prof. Sarah Trimpin, Wayne State University; Dr. Frank Gonzalez, National Cancer Institute; Dr. Devin Peterson, University of Minnesota; Caroline West and Eric Lesselier, University of Orleans; Professor Burt van Bavel, Orebro University; Professor Pauline Rudd, National Institute for Bioprocessing Research and Training; and Dr. Amit Kumar Mandal, St. John's Research Institute, Bangalore, India. These leading scientists, in partnership with Waters, are using liquid chromatography and mass spectrometry to help shape the future of scientific research and unlock the mysteries of science.