About the trial designThe Phase 1b trial design involved baseline safety and lung function testing on Day One followed by a one-hour intravenous infusion of placebo or 1200 micrograms MN-221. Safety, pharmacokinetic, and respiratory performance measurements were taken for the remainder of the day. Following a clinical investigator's evaluation early on Day Two, subjects received a treatment infusion every 12 hours through the morning of Day Four. Subjects were monitored until discharge on the morning of Day Five following a clinical investigator's examination. Clinical trial subjects received six treatment infusions over four days.
MediciNova Announces Positive Preliminary Results From A Multi-Day, Repeat-Dose Clinical Trial With MN-221 In Chronic Obstructive Pulmonary Disease Patients
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