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XenoPort Reports Second Quarter Financial Results

Selling, general and administrative expenses remained relatively constant for the second quarter and six months ended June 30, 2012, and were $7.6 million and $15.0 million, respectively, compared to $8.1 million and $15.8 million, respectively, for the same periods in 2011.

Net loss for the second quarter of 2012 was $8.0 million, compared to a net income of $19.5 million for the same period in 2011. Net loss for the six months ended June 30, 2012 was $17.1 million, compared to net income of $2.3 million for the same period in 2011. Basic and diluted net loss per share were both $0.22 in the second quarter of 2012 versus basic and diluted net income per share of $0.55 for the same period in the prior year. For the six-month period ended June 30, 2012, basic and diluted net loss per share were both $0.48 versus basic net income per share of $0.07 and diluted net income per share of $0.06 for the same period in 2011.

Conference Call

XenoPort will host a conference call at 5:00 p.m. Eastern Time today to discuss its financial results and provide an update of XenoPort’s business. To access the conference call via the Internet, go to To access the live conference call via phone, dial 1-888-275-3514. International callers may access the live call by dialing 706-679-1417. The reference number to enter the call is 15718592.

The replay of the conference call will be available for one week and may be accessed after 8:00 p.m. Eastern Time today via the Internet, at, or via phone at 1-800-642-1687 for domestic callers, or 706-645-9291 for international callers. The reference number to enter the replay of the call is 15718592.

About XenoPort

XenoPort is a biopharmaceutical company focused on developing and commercializing a portfolio of internally discovered product candidates for the potential treatment of neurological disorders. Horizant is approved in the United States for the treatment of RLS in adults and for the management of PHN in adults. GSK holds commercialization rights and certain development rights for Horizant in the United States. Regnite is approved for the treatment of RLS in adults in Japan. Astellas holds all development and commercialization rights for Regnite in Japan and five other Asian countries. XenoPort holds all other world-wide rights and has co-promotion and certain development rights to gabapentin enacarbil in the United States. XenoPort’s pipeline of product candidates includes potential treatments for patients with spasticity, Parkinson’s disease and relapsing-remitting multiple sclerosis.

To learn more about XenoPort, please visit the company Website at

Forward-Looking Statements

This press release contains “forward-looking” statements, including, without limitation, all statements related to Astellas’ expected commercialization and marketing efforts regarding Regnite; XenoPort’s XP21279 clinical development program and the timing and results thereof; XenoPort’s future pre-clinical studies and clinical trials and the timing thereof; FDA discussions, the regulatory process and the timing and outcome of regulatory actions; the potential for the filing of an NDA for XP21279 with the FDA under Section 505(b)(2); the suitability of XP21279 as a treatment for Parkinson’s disease; XenoPort’s XP23829 clinical development program and the timing and results thereof; the potential suitability of XP23829 as a treatment for relapsing-remitting MS and/or psoriasis; the potential of XP23829 to protect against neurodegeneration in preclinical models of Parkinson’s disease; the expectations of revenues based on product sales and the timing thereof; and the therapeutic and commercial potential of XenoPort’s preclinical and clinical product candidates. Any statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Words such as “believe,” “could,” “expect,” “future,” “goal,” “may,” “plans,” “possible,” “potential,” “proposed,” “will,” “would” and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon XenoPort's current expectations. Forward-looking statements involve risks and uncertainties. XenoPort's actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties, which include, without limitation, risks related to XenoPort’s dependence on Astellas to commercialize Regnite and GSK to commercialize Horizant; the uncertain results and timing of clinical trials and other studies; XenoPort’s ability to successfully conduct clinical trials in the anticipated timeframes, or at all; the uncertainty of the FDA’s review process and other regulatory requirements, including uncertainty as to whether the FDA would approve an NDA filed under Section 505(b)(2) and as to the requirements for acceptance and approval of any such filings; XenoPort’s dependence on its current and additional collaborative partners; the availability of resources to develop XenoPort’s product candidates; and the uncertain therapeutic and commercial value of XenoPort’s product candidates. These and other risk factors are discussed under the heading "Risk Factors" in XenoPort's Prospectus Supplement dated July 25, 2012 and filed with the Securities and Exchange Commission under Rule 424(b)(5) on July 26, 2012. XenoPort expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in the company's expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.

XENOPORT and Regnite are registered trademarks of XenoPort, Inc. Horizant is a registered trademark of GlaxoSmithKline.





(Unaudited, in thousands)

June 30,

December 31,
  2012     2011  
Current assets:
Cash and cash equivalents $ 21,115 $ 25,386
Short-term investments 60,633 69,056
Prepaids and other current assets   3,077     3,010  
Total current assets 84,825 97,452
Property and equipment, net 2,631 3,921
Restricted investments and other assets   2,232     2,663  
Total assets $ 89,688   $ 104,036  
Current liabilities $ 11,528 $ 13,530
Noncurrent liabilities   13,786     15,371  
Total liabilities   25,314     28,901  
Stockholders’ equity (deficit):
Common stock 36 35
Additional paid-in capital and other 502,227 495,886
Accumulated deficit   (437,889 )   (420,786 )
Total stockholders’ equity   64,374     75,135  
Total liabilities and stockholders’ equity $ 89,688   $ 104,036  





Three Months Ended June 30,

Six Months Ended June 30,
  2012       2011   2012       2011
(In thousands, except per share amounts)

Net revenue from unconsolidated joint operating activities
$ 10,000 $ 30,000 $ 10,000 $ 30,000
Collaboration revenue   379     7,379   10,758     7,758
Total revenues   10,379     37,379   20,758     37,758
Operating expenses:
Research and development* 10,804 9,904 22,982 19,758

Selling, general and administrative*
  7,589     8,075   14,989     15,826
Total operating expenses   18,393     17,979   37,971     35,584
Income (loss) from operations (8,014 ) 19,400 (17,213 ) 2,174
Interest income   55     55   110     125
Net income (loss) $ (7,959 ) $ 19,455 $ (17,103 ) $ 2,299

Basic net income (loss) per share
$ (0.22 ) $ 0.55 $ (0.48 ) $ 0.07

Diluted net income (loss) per share
$ (0.22 ) $ 0.55 $ (0.48 ) $ 0.06

Shares used to compute basic net income (loss) per share
  35,794     35,400   35,712     35,336

Shares used to compute diluted net income (loss) per share
  35,794     35,635   35,712     35,665

* Includes employee non-cash stock-based compensation, as follows:

Research and development









Selling, general and administrative





Total non-cash stock-based compensation expense









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