This account is pending registration confirmation. Please click on the link within the confirmation email previously sent you to complete registration.
Need a new registration confirmation email? Click here
TheStreet Open House

Affymetrix Launches Advanced RNA Amplification Technology For Whole-Genome Expression Analysis Of FFPE Samples

Stock quotes in this article: AFFX

Affymetrix, Inc. (NASDAQ:AFFX) announced today the availability of SensationPlus™ FFPE Amplification and 3’ IVT Labeling Kit (SensationPlus™ FFPE Reagent Kit), consisting of RNA amplification and labeling modules, to enable gene expression profiling of formalin-fixed, paraffin-embedded (FFPE) samples on GeneChip® 3’ IVT arrays and Almac XcelTM Array for disease clinical research and retrospective studies.

SensationPlus TM FFPE Reagent Kit is an advanced version of the Genisphere ® technology Affymetrix licensed last year. This technology has been significantly optimized to overcome the challenges associated with analyzing archived FFPE samples, especially those as old as a decade or more. The kit efficiently generates sufficient target from as little as 20 ng of FFPE-derived total RNA for complete gene expression profiling applications such as biomarker discovery and validation. This robust RNA amplification and labeling solution combined with a range of 3’ IVT microarrays offered from Affymetrix – Almac Xcel™ Array, GeneChip ® Human Genome U133 Plus 2.0 Array, and GeneChip ® PrimeView™ Human Gene Expression Array – offers unparalleled sensitivity, reproducibility, and performance, enabling researchers to maximize their discovery from their precious FFPE samples.

“Affymetrix’ SensationPlus TM FFPE Reagent Kit represents a simple solution for difficult FFPE samples,” said Ryan Davis at the Genomics Shared Resource, University of California, Davis Comprehensive Cancer Center. “Using this kit’s quick and user-friendly protocol with minimal sample input, we were able to reliably amplify FFPE-derived RNA where reagent kits from other vendors had failed, enabling us to obtain meaningful gene expression data from Affymetrix’ GeneChip ® Human Genome U133 Plus 2.0 Array.”

“This new product launch advances Affymetrix’ vision of growing our microarray business with targeted applications where array-based approaches provide more cost-effective solutions, highly accurate data, and the most relevant gene expression content compared to competing technologies,” said Kevin Cannon, PhD, General Manager & VP of the Expression Business Unit at Affymetrix. “In today’s competitive market, it is critical to provide researchers with the right tool for the specific application. The strategic launch of SensationPlus TM FFPE Reagent Kit is a perfect complement to the Affymetrix microarray portfolio, providing researchers with proven and validated performance as well as a complete workflow solution for whole-genome analysis from their precious FFPE samples. Combined with our QuantiGene ® Assays for single or multiplex quantification of RNA targets as well as in situ visualization of RNA, Affymetrix is able to provide a complete portfolio of products for biomarker discovery and validation.”

It is estimated that there are more than 1 billion FFPE samples, an untapped resource of valuable data for academic, pharmaceutical, and biotechnology researchers doing translational research and translational medicine studies. These samples, often of varying ages and tissue types, may include information on the clinical outcome and are optimal for retrospective studies in areas such as biomarker discovery, disease progression analysis, and other clinical studies.

1 of 2

Select the service that is right for you!

COMPARE ALL SERVICES
Action Alerts PLUS
Try it NOW

Jim Cramer and Stephanie Link actively manage a real portfolio and reveal their money management tactics while giving advanced notice before every trade.

Product Features:
  • $2.5+ million portfolio
  • Large-cap and dividend focus
  • Intraday trade alerts from Cramer
  • Weekly roundups
TheStreet Quant Ratings
Try it NOW
Only $49.95/yr

Access the tool that DOMINATES the Russell 2000 and the S&P 500.

Product Features:
  • Buy, hold, or sell recommendations for over 4,300 stocks
  • Unlimited research reports on your favorite stocks
  • A custom stock screener
  • Upgrade/downgrade alerts
Stocks Under $10
Try it NOW

David Peltier, uncovers low dollar stocks with extraordinary upside potential that are flying under Wall Street's radar.

Product Features:
  • Model portfolio
  • Stocks trading below $10
  • Intraday trade alerts
  • Weekly roundups
Dividend Stock Advisor
Try it NOW

Jim Cramer's protege, David Peltier, identifies the best of breed dividend stocks that will pay a reliable AND significant income stream.

Product Features:
  • Diversified model portfolio of dividend stocks
  • Alerts when market news affect the portfolio
  • Bi-weekly updates with exact steps to take - BUY, HOLD, SELL
Real Money Pro
Try it NOW

All of Real Money, plus 15 more of Wall Street's sharpest minds delivering actionable trading ideas, a comprehensive look at the market, and fundamental and technical analysis.

Product Features:
  • Real Money + Doug Kass Plus 15 more Wall Street Pros
  • Intraday commentary & news
  • Ultra-actionable trading ideas
Options Profits
Try it NOW

Our options trading pros provide daily market commentary and over 100 monthly option trading ideas and strategies to help you become a well-seasoned trader.

Product Features:
  • 100+ monthly options trading ideas
  • Actionable options commentary & news
  • Real-time trading community
  • Options TV
To begin commenting right away, you can log in below using your Disqus, Facebook, Twitter, OpenID or Yahoo login credentials. Alternatively, you can post a comment as a "guest" just by entering an email address. Your use of the commenting tool is subject to multiple terms of service/use and privacy policies - see here for more details.
Submit an article to us!
DOW 16,806.28 -236.62 -1.39%
S&P 500 1,943.91 -28.38 -1.44%
NASDAQ 4,414.70 -78.69 -1.75%

Brokerage Partners

Rates from Bankrate.com

  • Mortgage
  • Credit Cards
  • Auto

Free Newsletters from TheStreet

My Subscriptions:

After the Bell

Before the Bell

Booyah! Newsletter

Midday Bell

TheStreet Top 10 Stories

Winners & Losers

Register for Newsletters
Top Rated Stocks Top Rated Funds Top Rated ETFs