At the Alzheimer’s Association International Conference in Vancouver, Canada July 15-19, 2012, data from the ELND005 Phase 2 trials in mild/moderate Alzheimer’s disease describing its effect on both brain scyllo-inositol and myo-inositol levels were presented. In addition, data were also presented on the effects of oral ELND005 on neuropsychiatric symptoms in the Phase 2 trials and the potential role of myo-inositol reduction.
In the second quarter, Elan and Proteostasis Therapeutics, Inc. (Proteostasis) terminated their Strategic Alliance and License Agreement. Elan retains its approximate 24% equity interest in Proteostasis.
Other net charges
Other net charges for the three and six months ended June 30, 2012 and 2011 were as follows:
Three Months Ended June 30
Six Months Ended June 30
|1.5||—||Severance, restructuring and other costs||1.9||1.4|
|0.8||(0.1)||Facilities and other asset impairment charges||2.7||0.5|
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